Document Detail

Medianecrosis of the aorta (MNA)--Gsell-Erdheim syndrome: main histopathological features.
MedLine Citation:
PMID:  16092669     Owner:  NLM     Status:  MEDLINE    
Twenty four cases of Gsell-Erdheim syndrome observed in 1999-2001 have been examined. There were 20 men (83.4%) and 4 women (16.6%). The age ranged from 22 to 69 years but 6 men (25%) died at age under 50. The following variants of aortic lesions were revealed in autopsy material: intimal tear with the following dissection which extends along the aorta to variable distances--in most cases into iliac arteries. The morphologic changes, associated with were: anuclear zones, elastolysis, thinning, dyschromia and fragmentation of elastic fibers, focal hyperelastosis. Such changes were revealed in all parts of the aortic wall, independently of the site of rupture.
Dmytrij Zerbino; Julia Kusik; Elena Havrilyuk
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Polish journal of pathology : official journal of the Polish Society of Pathologists     Volume:  56     ISSN:  1233-9687     ISO Abbreviation:  Pol J Pathol     Publication Date:  2005  
Date Detail:
Created Date:  2005-08-11     Completed Date:  2005-09-06     Revised Date:  2007-08-01    
Medline Journal Info:
Nlm Unique ID:  9437432     Medline TA:  Pol J Pathol     Country:  Poland    
Other Details:
Languages:  eng     Pagination:  75-9     Citation Subset:  IM    
Institute of Clinical Pathology, Danylo Halytsky Lviv State Medical University, Lviv, Ukraine.
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MeSH Terms
Aneurysm, Dissecting / etiology*,  pathology
Aorta / pathology*
Aortic Aneurysm / etiology*,  pathology
Elastic Tissue / pathology
Middle Aged
Necrosis / complications*,  pathology
Tunica Media / pathology*

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