Document Detail


Medial medullary infarct aggravates central poststroke pain caused by previous lateral medullary infarct.
MedLine Citation:
PMID:  17483584     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Although the pathogenesis of central poststroke pain (CPSP) remains obscure, interactions between the spinothalamic tract and lemniscal sensory tract may be involved in its pathogenic mechanism. CASE DESCRIPTION: A patient developed lateral medullary infarction, which produced contralateral spinothalamic sensory deficits and subsequent CPSP. The CPSP gradually improved until the development of ipsilateral medial medullary infarction 26 months later, which was associated with mild hemiparesis and lemniscal sensory deficits. The ipsilateral medial medullary infarction immediately aggravated the CPSP to its previous level. CONCLUSION: This observation has implications regarding the pathogenesis of CPSP. CPSP may be related to hyperexcitation of the spinothalamic pathway by the reticulothalamic system, which in turn is modulated by the medial lemniscus pathway.
Authors:
Jong S Kim
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Publication Detail:
Type:  Case Reports; Journal Article; Research Support, Non-U.S. Gov't     Date:  2007-05-04
Journal Detail:
Title:  European neurology     Volume:  58     ISSN:  1421-9913     ISO Abbreviation:  Eur. Neurol.     Publication Date:  2007  
Date Detail:
Created Date:  2007-07-13     Completed Date:  2007-08-23     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0150760     Medline TA:  Eur Neurol     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  41-3     Citation Subset:  IM    
Copyright Information:
Copyright 2007 S. Karger AG, Basel.
Affiliation:
Department of Neurology, University of Ulsan, Asan Medical Center, Seoul, South Korea. jongskim@amc.seoul.kr
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MeSH Terms
Descriptor/Qualifier:
Humans
Lateral Medullary Syndrome / complications*,  pathology
Magnetic Resonance Imaging
Male
Medulla Oblongata / pathology*
Middle Aged
Models, Biological
Pain / etiology*,  pathology
Pain Measurement

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