Document Detail


Medial arterial calcification mimicking temporal arteritis.
MedLine Citation:
PMID:  15384038     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Medial arterial calcification, which has been increasingly recognized in end-stage renal disease (ESRD) patients, has been associated with acutely symptomatic vascular complications including calcific uremic arteriolopathy (calciphylaxis) and ischemic changes in the extremities. This report describes a 50-year-old ESRD patient on maintenance hemodialysis in whom medial arterial calcification developed with features mimicking the findings of temporal arteritis. He complained of persistent bilateral temporal area headaches with associated symptoms of blurred vision; pain in his shoulders, hips, and knees; and intermittent symptoms consistent with jaw claudication. He was not receiving calcium or vitamin D supplements. Superficial temporal arteries were dilated, tortuous, nodular, and tender to palpation. Ophthalmologic examination was unremarkable, except for the presence of peripapillary atrophy. Temporal artery biopsy results showed medial arterial calcification with mild inflammatory changes. No giant cells were identified. Additional long-term complications of medial arterial calcification have included the development of painful ischemic ulceration of the glans penis and extensive mitral annulus calcification detected by echocardiography. The findings in this patient show that clinical manifestations of medial artery calcification associated with ESRD can mimic those seen with other vascular diseases.
Authors:
Ahmed I Al-Absi; Barry M Wall; C Robert Cooke
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  American journal of kidney diseases : the official journal of the National Kidney Foundation     Volume:  44     ISSN:  1523-6838     ISO Abbreviation:  Am. J. Kidney Dis.     Publication Date:  2004 Oct 
Date Detail:
Created Date:  2004-09-22     Completed Date:  2005-03-01     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  8110075     Medline TA:  Am J Kidney Dis     Country:  United States    
Other Details:
Languages:  eng     Pagination:  e73-8     Citation Subset:  IM    
Affiliation:
Department of Nephrology, University of Tennessee Health Science Center, Veterans Affairs Medical Center, Memphis, TN 38104, USA.
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MeSH Terms
Descriptor/Qualifier:
Arteriosclerosis / complications*,  diagnosis*,  pathology
Diagnosis, Differential
Giant Cell Arteritis / diagnosis*
Humans
Kidney Failure, Chronic / complications*,  therapy
Male
Middle Aged
Renal Dialysis

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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