Document Detail


Medallion-like dermal dendrocyte hamartoma: a new clinically and histopathologically distinct lesion.
MedLine Citation:
PMID:  15337977     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Dermal dendrocyte hamartomas are extremely rare; only two examples have been described with clinical features different from our cases and with incomplete immunohistochemical characterization. We report three female patients presenting a medallion-shaped, well-defined, slightly atrophic and asymptomatic congenital lesion. All 3 patients showed a fusiform-cell proliferation. Immunohistochemistry was positive for CD34, factor XIIIa, and fascin. Electron microscopy showed typical features of dermal dendrocytes. We believe that the lesions described represent a new, clinically and histopathologically distinct lesion originating in dermal dendrocytes. We propose to name it medallion-like dermal dendrocyte hamartoma.
Authors:
Rodolfo Rodríguez-Jurado; Carolina Palacios; Carola Durán-McKinster; Patricia Mercadillo; Luz Orozco-Covarrubias; Maria del Mar Saez-de-Ocariz; Ramón Ruiz-Maldonado
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of the American Academy of Dermatology     Volume:  51     ISSN:  1097-6787     ISO Abbreviation:  J. Am. Acad. Dermatol.     Publication Date:  2004 Sep 
Date Detail:
Created Date:  2004-08-31     Completed Date:  2005-03-17     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7907132     Medline TA:  J Am Acad Dermatol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  359-63     Citation Subset:  IM    
Affiliation:
Department of Pathology, National Institute of Pediatrics, Mexico.
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MeSH Terms
Descriptor/Qualifier:
Antigens, CD34 / analysis
Carrier Proteins / analysis
Child
Diagnosis, Differential
Factor XIIIa / analysis
Female
Hamartoma / classification,  congenital,  metabolism,  pathology*
Humans
Microfilament Proteins / analysis
Microscopy, Electron
Neurofibroma / diagnosis
Skin Diseases / classification,  congenital,  metabolism,  pathology*
Vimentin / analysis
Chemical
Reg. No./Substance:
0/Antigens, CD34; 0/Carrier Proteins; 0/Microfilament Proteins; 0/Vimentin; 146808-54-0/fascin; EC 2.3.2.13/Factor XIIIa

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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