Document Detail

Meconium passage in very-low-birth-weight infants.
MedLine Citation:
PMID:  8301808     Owner:  NLM     Status:  MEDLINE    
The timing of the first meconium stool has been considered a marker for proper gastrointestinal functioning in the term infant. There is limited information on the meconium passage patterns of very-low-birth-weight infants of less than 32 weeks' gestation. It is unknown whether feeding practices influence the timing of the first stool in these infants. We retrospectively studied 47 very-low-birth-weight infants with birth weights of 1250 g or less who were previously enrolled in a study of gastrointestinal (GI) priming. Infants whose mothers desired to breast feed (n = 7) were given GI priming with their own mother's milk. The remaining infants had been randomly assigned to receive total parenteral nutrition alone (n = 21) or GI priming with infant formula (n = 19) during the first 14 days of life. We attempted to advance all infants to full enteral nutrition by 21 days of age. There was no statistically significant difference in timing of the first stool among the three groups. The overall median age at first stool was 43 hours, and the 75th percentile was 10 days. The range was 1/2 hour to 27 days. There was no concordance between time of first stool and birth weight within the range studied. There was no concordance between time of first stool and necrotizing enterocolitis, although there was little statistical power to detect this. There was also very little concordance with feeding tolerance. Other than necrotizing enterocolitis, no significant GI disease developed in any of the infants studied.(ABSTRACT TRUNCATED AT 250 WORDS)
W H Meetze; V L Palazzolo; D Bowling; M Behnke; D J Burchfield; J Neu
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Publication Detail:
Type:  Clinical Trial; Journal Article; Randomized Controlled Trial; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  JPEN. Journal of parenteral and enteral nutrition     Volume:  17     ISSN:  0148-6071     ISO Abbreviation:  JPEN J Parenter Enteral Nutr     Publication Date:    1993 Nov-Dec
Date Detail:
Created Date:  1994-03-04     Completed Date:  1994-03-04     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  7804134     Medline TA:  JPEN J Parenter Enteral Nutr     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  537-40     Citation Subset:  IM    
University of Florida College of Medicine, Gainesville.
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MeSH Terms
Birth Weight
Breast Feeding
Gastrointestinal Motility*
Infant Food
Infant Nutritional Physiological Phenomena*
Infant, Low Birth Weight / physiology*
Infant, Newborn
Infant, Premature / physiology*
Meconium / physiology*
Milk, Human
Parenteral Nutrition, Total
Retrospective Studies
Grant Support

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