Document Detail

Meconium in the amniotic fluid and fetal acid-base status.
MedLine Citation:
PMID:  2911423     Owner:  NLM     Status:  MEDLINE    
Of 323 pregnancies with meconium-stained amniotic fluid at 36-42 weeks' gestation, 68 (21%) had a pH less than 7.20 in umbilical arterial blood, 21 (7%) had a pH less than 7.15, and only three newborns (0.9%) had true metabolic acidemia. At birth, of the 74 newborns with normal electronic fetal heart rate (FHR) tracings, eight (11%) had an umbilical arterial pH less than 7.20. There was a significantly higher frequency of acidemia (defined as pH less than 7.20) in newborns with both baseline and periodic FHR abnormalities. Although there was a significant difference (P less than .05) in the frequency of meconium found below the cords in these neonates with an umbilical artery pH less than 7.20 compared with those with values exceeding 7.20, there was no significant difference in the frequency of clinical meconium aspiration syndrome. We conclude that meconium-stained amniotic fluid correlates poorly with infant condition at birth as reflected by umbilical cord acid-base measurements.
E R Yeomans; L C Gilstrap; K J Leveno; J S Burris
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Obstetrics and gynecology     Volume:  73     ISSN:  0029-7844     ISO Abbreviation:  Obstet Gynecol     Publication Date:  1989 Feb 
Date Detail:
Created Date:  1989-02-23     Completed Date:  1989-02-23     Revised Date:  2009-10-26    
Medline Journal Info:
Nlm Unique ID:  0401101     Medline TA:  Obstet Gynecol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  175-8     Citation Subset:  AIM; IM    
Department of Obstetrics and Gynecology, University of Texas Southwestern Medical School, Dallas.
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MeSH Terms
Acid-Base Imbalance / diagnosis*
Amniotic Fluid / analysis*
Apgar Score
Asphyxia Neonatorum / diagnosis*
Fetal Blood / analysis
Fetal Diseases / diagnosis*
Hydrogen-Ion Concentration
Infant, Newborn
Meconium / analysis*

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