Document Detail


Meconium aspiration in the midtrimester fetus: an autopsy study.
MedLine Citation:
PMID:  19323599     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We studied the incidence, severity, and significance of intrauterine meconium aspiration (IUMA) in the midtrimester fetus. Lung sections from 219 midtrimester fetuses were examined for meconium, identified by finding meconium corpuscles. There were 21 cases (9.6%) with IUMA. Gestational age ranged from 13 to 23 weeks (mean 18.7 weeks); 11 were female, and 10 were male. Eighteen were spontaneous abortions, 11 of which were macerated, and 1 of these was associated with an intrauterine contraceptive device. There were 3 terminations of pregnancy, 2 for fetal abnormality and 1 for severe preeclampsia. One fetus was conceived by in vitro fertilization. Fifteen cases (71.4%) showed slight IUMA, 5 cases (23.8%) showed moderate IUMA, and in 1 case (4.8%) IUMA was massive. The incidence of IUMA in an autopsy series of midtrimester fetuses was 9.6%. The amount of aspirated meconium was usually small and possibly physiologic. When IUMA was moderate or massive, it was associated with severe abnormality of the umbilical cord or placenta, particularly subchorionic hematoma.
Authors:
Elin Mortensen; Michael Shelley Kearney
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society     Volume:  12     ISSN:  1093-5266     ISO Abbreviation:  Pediatr. Dev. Pathol.     Publication Date:    2009 Nov-Dec
Date Detail:
Created Date:  2010-02-03     Completed Date:  2010-04-06     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9809673     Medline TA:  Pediatr Dev Pathol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  438-42     Citation Subset:  IM    
Affiliation:
Department of Pathology, University Hospital of North Norway, Troms?, Norway. elinmortensen@unn.no
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MeSH Terms
Descriptor/Qualifier:
Female
Fetus
Humans
Incidence
Infant, Newborn
Lung / pathology
Male
Meconium Aspiration Syndrome / epidemiology*,  pathology*
Placenta / pathology
Pregnancy
Pregnancy Trimester, Second
Umbilical Cord / pathology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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