| Mechanistic insight into polysaccharide use within the intestinal microbiota. | |
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MedLine Citation:
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PMID: 21637023 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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It is becoming increasingly clear that diet is one of the major factors that drives the function and composition of the intestinal microbiota. The diet of humans is highly diverse when considering different populations or even a single individual over a relatively short period of time. However, we are just beginning to understand the mechanisms that connect dietary change to intestinal microbiota dynamics. The community of microbes within our distal digestive tract influences numerous aspects of our biology, and aberrant shifts in its composition appear to be associated with several diseases. It is, therefore, necessary to understand how our behaviour and environmental factors, such as changes in diet, impact our intestinal residents. Here we look to recent work to highlight some of the major questions on the horizon for understanding the key role that the Bacteroidetes play in the commerce of dietary polysaccharides within the intestine. |
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Authors:
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David N Bolam; Justin L Sonnenburg |
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Publication Detail:
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Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review Date: 2011-03-01 |
Journal Detail:
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Title: Gut microbes Volume: 2 ISSN: 1949-0984 ISO Abbreviation: Gut Microbes Publication Date: 2011 Mar-Apr |
Date Detail:
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Created Date: 2011-06-22 Completed Date: 2011-10-04 Revised Date: 2012-03-01 |
Medline Journal Info:
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Nlm Unique ID: 101495343 Medline TA: Gut Microbes Country: United States |
Other Details:
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Languages: eng Pagination: 86-90 Citation Subset: IM |
Affiliation:
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Institute for Cell and Molecular Biosciences, Newcastle University, Medical School, Newcastle upon Tyne, UK. d.n.bolam@ncl.ac.ukl |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Bacteroidetes
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enzymology*,
metabolism* Gastrointestinal Tract / microbiology* Humans Models, Biological Polysaccharides / metabolism* |
| Grant Support | |
ID/Acronym/Agency:
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BBF0141631//Biotechnology and Biological Sciences Research Council; R01DK085025/DK/NIDDK NIH HHS |
| Chemical | |
Reg. No./Substance:
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0/Polysaccharides |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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