Document Detail

Mechanistic Insights into the Interface-Directed Transformation of Thiols into Disulfides and Molecular Hydrogen by Visible-Light Irradiation of Quantum Dots.
MedLine Citation:
PMID:  24470069     Owner:  NLM     Status:  Publisher    
Quantum dots (QDs) offer new and versatile ways to harvest light energy. However, there are few examples involving the utilization of QDs in organic synthesis. Visible-light irradiation of CdSe QDs was found to result in virtually quantitative coupling of a variety of thiols to give disulfides and H2 without the need for sacrificial reagents or external oxidants. The addition of small amounts of nickel(II) salts dramatically improved the efficiency and conversion through facilitating the formation of hydrogen atoms, thereby leading to faster regeneration of the ground-state QDs. Mechanistic studies reveal that the coupling reaction occurs on the QD surfaces rather than in solution and offer a blueprint for how these QDs may be used in other photocatalytic applications. Because no sacrificial agent or oxidant is necessary and the catalyst is reusable, this method may be useful for the formation of disulfide bonds in proteins as well as in other systems sensitive to the presence of oxidants.
Xu-Bing Li; Zhi-Jun Li; Yu-Ji Gao; Qing-Yuan Meng; Shan Yu; Richard G Weiss; Chen-Ho Tung; Li-Zhu Wu
Related Documents :
1433179 - 5,10-methylenetetrahydro-5-deazafolic acid and analogues: synthesis and biological acti...
15104489 - Mycobacterium tuberculosis growth inhibition by constituents of sapium haematospermum.
20085279 - Anti-inflammatory activity of new compounds from andrographis paniculata by nf-kappab t...
7575639 - Inhibition of 2,3-oxidosqualene cyclase and sterol biosynthesis by 10- and 19-azasquale...
21049929 - Design, synthesis, and evaluation of diarylpyridines and diarylanilines as potent non-n...
20056549 - Discovery of 3-(4-bromophenyl)-6-nitrobenzo[1.3.2]dithiazolium ylide 1,1-dioxide as a n...
18459809 - Improved procedure for the synthesis of enamine n-oxides.
3026379 - An esr study on lipid peroxidation process. formation of hydrogen atoms and hydroxyl ra...
22982119 - Synthesis and biological activity of obatoclax derivatives as novel and potent shp-1 ag...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2014-1-27
Journal Detail:
Title:  Angewandte Chemie (International ed. in English)     Volume:  -     ISSN:  1521-3773     ISO Abbreviation:  Angew. Chem. Int. Ed. Engl.     Publication Date:  2014 Jan 
Date Detail:
Created Date:  2014-1-28     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0370543     Medline TA:  Angew Chem Int Ed Engl     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Neurobiological Mechanisms for Impulsive-Aggression: The Role of MAOA.
Next Document:  Common Sense of Experts : Social Representations of Justice Amongst Professionals.