Document Detail

Mechanisms of virus-induced immune suppression.
MedLine Citation:
PMID:  2986813     Owner:  NLM     Status:  MEDLINE    
The recent demonstration that the acquired immune deficiency syndrome (AIDS) is caused by a retrovirus that affects humans has given rise to widespread concern about the immunosuppressive properties of viruses in general. A wide variety of viruses have been shown to be able to compromise immune function. Sometimes immunosuppression results from the pathologic processes that viruses are able to induce. In other instances virus-induced immune derangements may themselves be responsible for the onset of pathologic change. In some cases a single infectious viral agent may be able to modulate several immunologic mechanisms simultaneously. This review discusses some of the various complex mechanisms through which viral infections can alter the function of the immune system.
M A Wainberg; E L Mills
Related Documents :
17168793 - Complex effect of adenovirus early region proteins on innate immune system.
19649323 - Influence of dendritic cells on viral pathogenicity.
17301063 - Cellular vitamin c increases chromate toxicity via a death program requiring mismatch r...
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  Canadian Medical Association journal     Volume:  132     ISSN:  0008-4409     ISO Abbreviation:  Can Med Assoc J     Publication Date:  1985 Jun 
Date Detail:
Created Date:  1985-07-22     Completed Date:  1985-07-22     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0414110     Medline TA:  Can Med Assoc J     Country:  CANADA    
Other Details:
Languages:  eng     Pagination:  1261-7     Citation Subset:  AIM; IM; X    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Acquired Immunodeficiency Syndrome / immunology,  microbiology
Burkitt Lymphoma / immunology
Cell Transformation, Viral
Cytomegalovirus Infections / immunology
Herpesvirus 4, Human / immunology
Immunity, Cellular
Interleukin-2 / immunology*
Killer Cells, Natural / immunology,  microbiology
T-Lymphocytes / immunology,  microbiology*
Virus Diseases / immunology*
Viruses / immunology
Reg. No./Substance:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Surgical management of the patient at high risk for breast cancer.
Next Document:  Establishment and characterization of neoplastic cells from a malignant fibrous histiocytoma. A poss...