Document Detail


Mechanisms of twinning. II. Laterality and intercellular bonding in monozygotic twinning.
MedLine Citation:
PMID:  11396375     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: To utilize observations on laterality and handedness to gain insight into the initiating mechanism of monozygotic human quadruplets. STUDY DESIGN: In a study of thumbprints and handedness in sets of monozygotic quadruplets, homolateral and heterolateral comparisons were used to distinguish mirror-image from symmetric divisions. RESULTS: Data were consistent with a mechanism involving a mirror-image duplication in the first division and a subsequent symmetric separation of the daughters. In addition, these data failed to substantiate a genetic linkage between dermatoglyphics and handedness. CONCLUSION: Reported and reviewed data tend to support the analogy of monozygotic polyembryony in armadillos and humans. The plausible roles of delayed implantation and intercellular bonding are explored, especially as they relate to ambient calcium concentration. Factors tending to enhance the likelihood of monozygotic twinning include calcium channel blockers, lactation, ovulation induction and prolonged in vitro fertilization incubation.
Authors:
G Steinman
Related Documents :
15270925 - Comparison of ultrasound and magnetic resonance imaging in 100 singleton pregnancies wi...
20499405 - Frequency and cause of disagreements in imaging diagnosis in children with ventriculome...
20981415 - Development of laminar organization of the fetal cerebrum at 3.0t and 7.0t: a postmorte...
12905505 - Learning curve for sonographic examination of the fetal nasal bone at 11-14 weeks.
22119745 - Voxel based morphometric and diffusion tensor imaging analysis in male bipolar patients...
24450675 - Accuracy of multiparametric mri for prostate cancer detection: a meta-analysis.
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Journal of reproductive medicine     Volume:  46     ISSN:  0024-7758     ISO Abbreviation:  J Reprod Med     Publication Date:  2001 May 
Date Detail:
Created Date:  2001-06-08     Completed Date:  2001-10-11     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0173343     Medline TA:  J Reprod Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  473-9     Citation Subset:  IM    
Affiliation:
Department of Obstetrics and Gynecology, Long Island Jewish Medical Center, New Hyde Park, New York, USA. dav4601@aol.com
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Dermatoglyphics*
Female
Functional Laterality / genetics*
Humans
Linkage (Genetics)
Pregnancy
Pregnancy, Multiple*
Twins, Monozygotic / genetics*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Mechanisms of twinning. I. Effect of environmental diversity on genetic expression in monozygotic mu...
Next Document:  Natural history of twin-twin transfusion syndrome.