Document Detail

Mechanisms and significance of QRS macrovoltage in the absence of cardiac hypertrophy.
MedLine Citation:
PMID:  101995     Owner:  NLM     Status:  MEDLINE    
The electric stimulation of the lateral ventricular walls carried out in experiments on dog heart (open-thorax), as well as the analysis of the clinical, radiological and electrocardiographic data recorded in 462 cases with QRS macrovoltage led to the following conclusions: a) in 22% of the cases (hospital cardiologic examinations) this anomaly cannot be accounted for either by age, blood pressure or cardiac hypertrophy; b) a temporarily perturbed development of the ventricular depolarization, i.e. a "jerky" depolarization, not stagnant enough to produce an intraventricular block, may generate great negativity and positivity myocardial masses responsible for the appearance of large dipoles, namely of the increased QRS voltage; c) the coincident ischemia and macrovoltage of the QRS major wave, as well as the subsequent evolution of incipient CHD in a series of patients point to the hypothesis according to which the regional myocardial ischemia may induce a QRS macrovoltage by means of the above mechanism.
V Ionescu; L Stoenescu; R Stoenescu; P Stoiculescu; N Drăgulescu
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Physiologie     Volume:  15     ISSN:  1011-6206     ISO Abbreviation:  Physiologie     Publication Date:    1978 Jul-Sep
Date Detail:
Created Date:  1979-01-15     Completed Date:  1979-01-15     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  7510964     Medline TA:  Physiologie     Country:  ROMANIA    
Other Details:
Languages:  eng     Pagination:  161-70     Citation Subset:  IM    
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MeSH Terms
Arrhythmias, Cardiac / physiopathology
Coronary Disease / physiopathology*
Heart / physiopathology*
Middle Aged
Myocardial Contraction

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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