Document Detail


Mechanisms of selection and differentiation in germinal centers.
MedLine Citation:
PMID:  9099789     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The choice between death and survival, a feature of early B cell development, is a choice also faced by mature B cells. If they survive this early developmental decision, mature B cells then face a second choice: either to undergo either terminal differentiation into plasma cells or to differentiate into memory B cells. Antigens, T cell signals (cytokines, CD40 ligand and Fas ligand) as well as the activation state of B cells determine their ultimate fate.
Authors:
Y J Liu; O de Bouteiller; I Fugier-Vivier
Related Documents :
19247959 - A novel in vitro system for studying cardiomyocyte differentiation with medaka embryoni...
20665539 - Multilineage differentiation potential of cells isolated from the human amniotic membrane.
3163939 - Modulation of 6-thioguanine activity by guanine in human promyelocytic leukemia hl-60 c...
3089289 - Appearance of the arachidonic acid metabolic pathway in human promyelocytic leukemia (h...
20556569 - Induced differentiation of adipose-derived stromal cells into myoblasts.
1840889 - Differentiation and the establishment of cell type during sporulation in bacillus subti...
16510219 - Cardiac metastasis after squamous cell carcinoma of the oral cavity: case report.
17993169 - In search of mitochondrial mechanisms: interfield excursions between cell biology and b...
10224329 - Increased levels of sister chromatid exchanges in military aircraft pilots.
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Current opinion in immunology     Volume:  9     ISSN:  0952-7915     ISO Abbreviation:  Curr. Opin. Immunol.     Publication Date:  1997 Apr 
Date Detail:
Created Date:  1998-04-15     Completed Date:  1998-04-15     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  8900118     Medline TA:  Curr Opin Immunol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  256-62     Citation Subset:  IM    
Affiliation:
Schering-Plough, Laboratory for Immunological Research, Dardilly, France. HJ.Liu@sch-plough.fr
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
B-Lymphocytes / cytology*,  immunology
Cell Differentiation / genetics,  immunology
Germinal Center / immunology*
Humans
Mutation

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Immunoadhesins as research tools and therapeutic agents.
Next Document:  Hematopoietic stem cells: challenges to expectations.