Document Detail

Mechanisms and management of septic shock.
MedLine Citation:
PMID:  8490761     Owner:  NLM     Status:  MEDLINE    
Septic shock continues to be associated with high mortality. The systemic effects of severe infections are related to the release and activation of a myriad of mediator systems, central to which are bacterial toxins and cytokines. Therapy includes three facets--resuscitation, treatment of the underlying infection, and interventions directed at ameliorating mediator activity.
E C Rackow; M E Astiz
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Critical care clinics     Volume:  9     ISSN:  0749-0704     ISO Abbreviation:  Crit Care Clin     Publication Date:  1993 Apr 
Date Detail:
Created Date:  1993-06-17     Completed Date:  1993-06-17     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  8507720     Medline TA:  Crit Care Clin     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  219-37     Citation Subset:  IM    
Department of Medicine, St. Vincent's Hospital and Medical Center, New York, New York.
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MeSH Terms
Anti-Bacterial Agents / therapeutic use
Critical Care
Energy Metabolism
Immunologic Factors / therapeutic use
Lactates / blood
Lactic Acid
Oxygen / blood,  metabolism
Oxygen Consumption
Shock, Septic* / metabolism,  physiopathology,  therapy
Survival Rate
Reg. No./Substance:
0/Anti-Bacterial Agents; 0/Immunologic Factors; 0/Lactates; 50-21-5/Lactic Acid; 7782-44-7/Oxygen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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