Document Detail


Mechanisms of mammalian otoacoustic emission and their implications for the clinical utility of otoacoustic emissions.
MedLine Citation:
PMID:  15064654     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We review recent progress in understanding the physical and physiological mechanisms that generate otoacoustic emissions (OAEs). Until recently, the conceptual model underlying the interpretation of OAEs has been an integrated view that regards all OAEs as manifestations of cochlear nonlinearity. However, OAEs appear to arise by at least two fundamentally different mechanisms within the cochlea: nonlinear distortion and linear reflection. These differences in mechanism have be used to construct a new taxonomy for OAEs that identifies OAEs based on their mechanisms of generation rather than the details of their measurement. The mechanism-based taxonomy provides a useful conceptual framework for understanding and interpreting otoacoustic responses. As commonly measured in the clinic, distortion-product and other evoked OAEs comprise a mixtures of emissions produced by both mechanisms. This mixing precludes any fixed correspondence with the conventional, measurement-based nomenclature. We discuss consequences of the taxonomy for the clinical measurement and interpretation of OAEs.
Authors:
Christopher A Shera
Related Documents :
15086094 - Effect of enhancing curd formation during the first colostrum feed on absorption of gam...
6464704 - Mineralization in the newborn rat statoconia. an edax study.
21213294 - Human teratogens: update 2010.
22752764 - Fetomaternal hemorrhage in the second trimester.
19633554 - Outcome of pregnancy in patients with isolated proteinuria.
9660424 - Induction of spermatogenesis and achievement of pregnancy after microsurgical varicocel...
Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.; Review    
Journal Detail:
Title:  Ear and hearing     Volume:  25     ISSN:  0196-0202     ISO Abbreviation:  Ear Hear     Publication Date:  2004 Apr 
Date Detail:
Created Date:  2004-04-05     Completed Date:  2004-09-13     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  8005585     Medline TA:  Ear Hear     Country:  United States    
Other Details:
Languages:  eng     Pagination:  86-97     Citation Subset:  IM    
Affiliation:
Eaton-Peabody Laboratory of Auditory Physiology, Massachusetts Eye & Ear Infirmary, and Department of Otology & Laryngology, Harvard Medical School, Boston, Massachusetts 02114, USA. shera@epl.meei.harvard.edu
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Acoustic Stimulation*
Animals
Hearing Disorders / diagnosis*
Hearing Tests* / methods
Humans
Linear Models
Mammals / physiology*
Nonlinear Dynamics
Otoacoustic Emissions, Spontaneous / physiology*
Grant Support
ID/Acronym/Agency:
DC03687/DC/NIDCD NIH HHS
Comments/Corrections
Erratum In:
Ear Hear. 2004 Jun;25(3):308

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Prehension synergies.
Next Document:  Dead regions in the cochlea: conceptual foundations, diagnosis, and clinical applications.