Document Detail


Mechanisms of injury to white matter adjacent to a large intraventricular hemorrhage in the preterm brain.
MedLine Citation:
PMID:  20232402     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The purpose of this article is to investigate the hyperechoic lesion seen adjacent to a lateral ventricle that contains blood but is not distended. The literature on ependymal barrier dysfunction was reviewed in search of mechanisms of injury to the white matter adjacent to an intraventricular hemorrhage. The clinical literature on the clinical diagnosis of periventricular hemorrhagic infarction was also reviewed to find out how frequently this diagnosis was made. Support was found for the possibility that the ventricular wall does not always function as an efficient barrier, allowing ventricular contents to gain access to the white matter where they cause damage. Hemorrhagic infarction may not be the only or the most frequent mechanism of white matter damage adjacent to a large intraventricular hemorrhage.
Authors:
Ira Adler; Dan Batton; Bradford Betz; Steven Bezinque; Kirsten Ecklund; Joseph Junewick; Roy McCauley; Cindy Miller; Joanna Seibert; Barbara Specter; Sjirk Westra; Alan Leviton
Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Review    
Journal Detail:
Title:  Journal of clinical ultrasound : JCU     Volume:  38     ISSN:  1097-0096     ISO Abbreviation:  J Clin Ultrasound     Publication Date:  2010 Jun 
Date Detail:
Created Date:  2010-05-12     Completed Date:  2010-08-12     Revised Date:  2013-05-29    
Medline Journal Info:
Nlm Unique ID:  0401663     Medline TA:  J Clin Ultrasound     Country:  United States    
Other Details:
Languages:  eng     Pagination:  254-8     Citation Subset:  IM    
Affiliation:
Eastern Radiologists, Greenville, NC 27834, USA.
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MeSH Terms
Descriptor/Qualifier:
Cerebral Hemorrhage / complications,  ultrasonography*
Cerebral Ventricles / ultrasonography*
Echoencephalography / methods*
Humans
Infant, Newborn
Infant, Premature, Diseases / ultrasonography*
Inflammation / etiology,  ultrasonography
Grant Support
ID/Acronym/Agency:
1 U01 NS 40069-01A2/NS/NINDS NIH HHS; P30-HD-18655/HD/NICHD NIH HHS; U01 NS040069-01A2/NS/NINDS NIH HHS
Comments/Corrections

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