Document Detail

Mechanisms and evidence for the role of enhanced external counterpulsation in heart failure management.
MedLine Citation:
PMID:  16684494     Owner:  NLM     Status:  MEDLINE    
Balloon counterpulsation has gained widespread acceptance as a therapy for cardiogenic shock. However, over the past four decades a parallel method of noninvasive counterpulsation, enhanced external counterpulsation (EECP), has been defined and developed. Mechanisms of benefit for this technology continue to emerge and include enhanced coronary and other key target organ perfusion beds. Other mechanisms include angiogenesis and enhanced cellular metabolism. Beyond putative mechanisms there is ample evidence for improved and sustained outcomes in patients with and without left ventricular dysfunction. This evidence comes from long-term registry reports and randomized clinical trials. With respect to heart failure (HF), there is registry, pilot trial, and randomized clinical trial evidence of safety and efficacy. This paper summarizes some of the mechanisms and outcomes of EECP in HF patients and helps to elucidate the role of EECP in the management of patients with chronic HF.
Marc A Silver
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Current heart failure reports     Volume:  3     ISSN:  1546-9530     ISO Abbreviation:  Curr Heart Fail Rep     Publication Date:  2006 Apr 
Date Detail:
Created Date:  2006-05-10     Completed Date:  2006-10-03     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  101196487     Medline TA:  Curr Heart Fail Rep     Country:  United States    
Other Details:
Languages:  eng     Pagination:  25-32     Citation Subset:  IM    
Advocate Christ Medical Center, Suite 319 South, Oak Lawn, IL 60453, USA.
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MeSH Terms
Counterpulsation / methods*
Heart Failure / therapy*
Quality of Life
Randomized Controlled Trials as Topic
Treatment Outcome
Ventricular Dysfunction, Left / therapy

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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