Document Detail


Mechanisms of dynamic cardiomyoplasty: current concepts.
MedLine Citation:
PMID:  8889879     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Dynamic cardiomyoplasty is an operation that is undergoing worldwide clinical evaluation. It had been developed to utilize the patient's own skeletal muscle to assist the failing heart. Although the clinical and quality of life benefits of cardiomyoplasty have been reported in most patients, the results of quantitative hemodynamic analyses have been less consistent. This has prompted the reevaluation of the mechanisms of dynamic cardiomyoplasty other than simple cardiac compression by the wrapped muscle. There is good evidence to suggest that the following, either together or in part, comprise some of the mechanisms of dynamic cardiomyoplasty: (1) direct systolic assist; (2) myocardial (wall stress) sparing effect; (3) remodeling/girdling effect; and (4) angiogenesis. Current concepts and potential additional mechanisms are discussed and integrated, based on a review of the literature and our own recent studies.
Authors:
J H Oh; V Badhwar; R C Chiu
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Journal of cardiac surgery     Volume:  11     ISSN:  0886-0440     ISO Abbreviation:  J Card Surg     Publication Date:    1996 May-Jun
Date Detail:
Created Date:  1997-02-12     Completed Date:  1997-02-12     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8908809     Medline TA:  J Card Surg     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  194-9     Citation Subset:  IM    
Affiliation:
Division of Cardiothoracic Surgery, McGill University, Montreal, Canada.
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MeSH Terms
Descriptor/Qualifier:
Cardiomyoplasty*
Humans
Neovascularization, Physiologic
Sympathetic Nervous System / physiology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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