Document Detail


Mechanisms of chronic recurrent idiopathic ventricular tachycardia.
MedLine Citation:
PMID:  3373719     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In 24 patients with idiopathic ventricular tachycardia (VT), mechanisms of VT and the effects of antiarrhythmic drugs after induction were studied electrophysiologically, and by exercise testing. VT was induced electrophysiologically in 14 patients. Class 1 antiarrhythmic drugs were effective in 7 of them, which implied that one of the mechanisms of idiopathic VT was reentry related to the depressed channel dependent slow conduction. In 6 of the 14 patients, the QRS morphology of VT showed a complete RBBB with axis deviation pattern and the tachycardia was responsive to verapamil. In 2 of them, induction of VT was facilitated at low plasma verapamil concentrations. In the other 2 patients, left ventricular mapping showed that a notched potential preceding each QRS complex and the retrograde His bundle deflection with a short interval were recorded during VT. These findings suggested that the mechanism of this type of VT was reentry, mediated by Ca dependent slow conduction and located within the left bundle branch network. Exercise testing provoked VT in eight. Beta-blockers and Ca-antagonists were effective in 6 and in 4, respectively. These findings indicate the possibility that in addition to enhanced automaticity or reentry, triggered activity could play a role in the genesis of exercise related VT.
Authors:
M Sakurai; T Nishiono; I Yoshida; N Kato; H Yasuda
Related Documents :
9801479 - Interpretation of capnography.
11942589 - Prevalence of a shared isthmus in postinfarction patients with pleiomorphic, hemodynami...
21492089 - Exercise for the overweight and obese.
23558389 - Lactate kinetics at the lactate threshold in trained and untrained men.
6781209 - Effect of inspiration-expiration ratio on rebreathing with the mapleson d system (bain'...
2122169 - Using smoothing splines for detecting ventilatory thresholds.
21088549 - Does whole-body vibration training have acute residual effects on postural control abil...
3880189 - Prediction of distress for individuals wearing industrial respirators.
11323549 - Human hamstring muscles adapt to eccentric exercise by changing optimum length.
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Japanese circulation journal     Volume:  52     ISSN:  0047-1828     ISO Abbreviation:  Jpn. Circ. J.     Publication Date:  1988 Mar 
Date Detail:
Created Date:  1988-06-30     Completed Date:  1988-06-30     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7806868     Medline TA:  Jpn Circ J     Country:  JAPAN    
Other Details:
Languages:  eng     Pagination:  272-9     Citation Subset:  IM    
Affiliation:
Department of Cardiovascular Medicine, Hokkaido University School of Medicine; Sapporo, Japan.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Aged
Anti-Arrhythmia Agents / pharmacology*
Chronic Disease
Electrocardiography
Electrophysiology
Exercise Test
Female
Heart Ventricles / physiopathology
Humans
Male
Middle Aged
Recurrence
Tachycardia / physiopathology*
Chemical
Reg. No./Substance:
0/Anti-Arrhythmia Agents

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Effects of procainamide and lidocaine on electrically inducible ventricular tachycardia studied with...
Next Document:  Clinical significance of Vanghan Williams classification for treatment of ventricular tachycardia: s...