Document Detail


Mechanisms by which exercise training benefits patients with heart failure.
MedLine Citation:
PMID:  19352333     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Clinical consequences of heart failure are fatigue, dyspnea, and progressive impairment of exercise tolerance. Regular exercise training is associated with health-improving effects. In patients with stable heart failure, exercise training can relieve symptoms, improve exercise capacity and quality of life, as well as reduce hospitalization and, to some extent, risk of mortality. Progressive exercise training is associated with pulmonary, cardiovascular, and skeletal muscle metabolic adaptations that increase oxygen delivery and energy production. This Review focuses on current knowledge of mechanisms by which progressive and moderate exercise training can have sustained beneficial effects on patients with heart failure.
Authors:
Ettore Crimi; Louis J Ignarro; Francesco Cacciatore; Claudio Napoli
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Nature reviews. Cardiology     Volume:  6     ISSN:  1759-5010     ISO Abbreviation:  Nat Rev Cardiol     Publication Date:  2009 Apr 
Date Detail:
Created Date:  2009-04-08     Completed Date:  2009-07-06     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101500075     Medline TA:  Nat Rev Cardiol     Country:  England    
Other Details:
Languages:  eng     Pagination:  292-300     Citation Subset:  IM    
Affiliation:
Department of Anesthesia and Critical Care, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA. ecrimi@partners.org
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MeSH Terms
Descriptor/Qualifier:
Cardiovascular System / physiopathology
Endothelium, Vascular / physiopathology
Exercise Therapy*
Exercise Tolerance
Heart Failure / mortality,  physiopathology,  therapy*
Humans
Inflammation / prevention & control
Muscle, Skeletal / physiopathology
Nervous System / physiopathology
Quality of Life
Recovery of Function
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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