Document Detail


Mechanism of inactivation of hexokinase PII of Saccharomyces cerevisiae by D-xylose.
MedLine Citation:
PMID:  3309137     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The mechanism of inactivation of hexokinase PII of Saccharomyces cerevisiae by D-xylose was characterized. Inactivation was dependent on the presence of MgATP and was irreversible. Inactivation involved phosphorylation of the protein. Observation of the carbon catabolite repression of selected enzymes showed that invertase and maltase synthesis were not repressed when hexokinase PII was phosphorylated.
Authors:
R Fernández; P Herrero; M T Fernández; F Moreno
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of general microbiology     Volume:  132     ISSN:  0022-1287     ISO Abbreviation:  J. Gen. Microbiol.     Publication Date:  1986 Dec 
Date Detail:
Created Date:  1987-11-05     Completed Date:  1987-11-05     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0375371     Medline TA:  J Gen Microbiol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  3467-72     Citation Subset:  IM    
Affiliation:
Departamento Interfacultativo de Bioquimica, Facultad de Medicina, Universidad de Oviedo, Spain.
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MeSH Terms
Descriptor/Qualifier:
Adenosine Triphosphate / physiology
Enzyme Repression / drug effects
Hexokinase / antagonists & inhibitors*
Isoenzymes / antagonists & inhibitors*
Phosphates / metabolism
Saccharomyces cerevisiae / drug effects,  enzymology*
Xylose / pharmacology*
Chemical
Reg. No./Substance:
0/Isoenzymes; 0/Phosphates; 0/Xylose; 56-65-5/Adenosine Triphosphate; EC 2.7.1.1/Hexokinase

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