Document Detail

Mechanism of the appearance of nuclear inclusions with microfilaments and microtubules in sympathetic neurons. Influence of dibutyryl-adenosine 3'-5' monophosphate and theophylline
MedLine Citation:
PMID:  177138     Owner:  NLM     Status:  MEDLINE    
As we have shown previously the nucleus of sympathetic neurons contains microtubules and microfilaments giving rise to highly organized inclusions. Present in vivo experiments on cat stellate ganglia have shown that dibutyryl cyclic AMP and theophyllin induce an increase of their frequency (up to 8.5 fold). These and earlier observations lead us to conclude that cyclic AMP mediates the process of nuclear microtubules and microfilaments assembly from preformed protein subunits.
J Leonetti; R Seite; J Luciani-Vuillet; M Vio
Publication Detail:
Type:  English Abstract; In Vitro; Journal Article    
Journal Detail:
Title:  Bulletin de l'Association des anatomistes     Volume:  59     ISSN:  0376-6160     ISO Abbreviation:  Bull Assoc Anat (Nancy)     Publication Date:  1975 Sep 
Date Detail:
Created Date:  1976-07-06     Completed Date:  1976-07-06     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7503386     Medline TA:  Bull Assoc Anat (Nancy)     Country:  FRANCE    
Other Details:
Languages:  fre     Pagination:  651-6     Citation Subset:  IM    
Vernacular Title:
Recherches sur le mécanisme d'apparition des inclusions nucleaires à microfilaments et à microtubules des neurones sympathiques. Influence du dibutyryl-adénosine 3'-5' monophosphate cyclique et de la théophylline
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MeSH Terms
Bucladesine / pharmacology*
Cell Nucleus / drug effects*,  physiology,  ultrastructure
Microtubules / drug effects*,  physiology
Sympathetic Nervous System / ultrastructure*
Theophylline / pharmacology*
Reg. No./Substance:
362-74-3/Bucladesine; 58-55-9/Theophylline

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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