Document Detail

Mechanism of action of ketamine.
MedLine Citation:
PMID:  23866089     Owner:  NLM     Status:  In-Data-Review    
Ketamine induces rapid-onset and short-duration improvement in depressive and suicidal symptoms in both treatment-resistant unipolar depression and bipolar depression, and also reduces chronic pain after short intravenous infusions. In order to develop long-acting oral agents with the same clinical effects, the pharmacologic mechanism of action must be understood, and the leading hypotheses are discussed here.
Stephen M Stahl
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  CNS spectrums     Volume:  18     ISSN:  1092-8529     ISO Abbreviation:  CNS Spectr     Publication Date:  2013 Aug 
Date Detail:
Created Date:  2013-07-19     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9702877     Medline TA:  CNS Spectr     Country:  United States    
Other Details:
Languages:  eng     Pagination:  171-4     Citation Subset:  IM    
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