Document Detail


The Mechanism of Tissue-Restricted Antigen Gene Expression by AIRE.
MedLine Citation:
PMID:  23456700     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
The autoimmune regulator is a critical transcription factor for generating central tolerance in the thymus. Recent studies have revealed how the autoimmune regulator targets many otherwise tissue-restricted Ag genes to enable negative selection of autoreactive T cells.
Authors:
Kristina Zumer; Kalle Saksela; B Matija Peterlin
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of immunology (Baltimore, Md. : 1950)     Volume:  190     ISSN:  1550-6606     ISO Abbreviation:  J. Immunol.     Publication Date:  2013 Mar 
Date Detail:
Created Date:  2013-03-04     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  2985117R     Medline TA:  J Immunol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  2479-82     Citation Subset:  AIM; IM    
Affiliation:
Department of Virology, Haartman Institute, Helsinki University Central Hospital, University of Helsinki, FIN-00014 Helsinki, Finland.
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