| Mechanics of breathing after surgical ligation of patent ductus arteriosus in newborns with respiratory distress syndrome. | |
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MedLine Citation:
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PMID: 14631164 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The aim of the study was to detect changes in pulmonary function following ligation of a patent ductus arteriosus (PDA). Pulmonary function was recorded in 16 newborns (birth weight 1,081 +/- 166 g, gestational age 27.6 +/- 1.7 weeks) before and after ligation. No change in resistance of airways or mean airway pressure was observed. We found an increase in dynamic compliance (Cdyn) of 77% (p < 0.01), in tidal volume (TV) of 29% (p = 0.004), and in minute ventilation (MV) of 17% (p < 0.01) after the procedure. We demonstrated that pulmonary function improves after surgical ligation of the PDA. Because of considerable variation in intubated and spontaneously breathing premature newborns, we recommend the analysis of three main parameters: Cdyn, TV and MV for estimation of pulmonary mechanics in these infants. |
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Authors:
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Marta Szymankiewicz; Joan E Hodgman; Bijan Siassi; Janusz Gadzinowski |
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Publication Detail:
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Type: Journal Article Date: 2003-11-19 |
Journal Detail:
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Title: Biology of the neonate Volume: 85 ISSN: 0006-3126 ISO Abbreviation: Biol. Neonate Publication Date: 2004 |
Date Detail:
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Created Date: 2004-03-12 Completed Date: 2004-10-07 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0247551 Medline TA: Biol Neonate Country: Switzerland |
Other Details:
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Languages: eng Pagination: 32-6 Citation Subset: IM |
Copyright Information:
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Copyright 2004 S. Karger AG, Basel |
Affiliation:
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Department of Neonatology, University of Medical Sciences, Poznań, Poland. mszymank@gpsk.am.poznan.pl |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Airway Resistance Birth Weight Ductus Arteriosus, Patent / surgery* Female Gestational Age Humans Infant, Newborn Infant, Premature* Ligation Lung Compliance Male Respiration, Artificial Respiratory Distress Syndrome, Newborn / physiopathology* Respiratory Mechanics / physiology* Tidal Volume Treatment Outcome |
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