Document Detail


Mechanical and pharmacologic catheter-directed thrombolysis treatment of severe, symptomatic, bilateral deep vein thrombosis with congenital absence of the inferior vena cava.
MedLine Citation:
PMID:  21609802     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We report the use of mechanical and pharmacologic catheter-directed thrombolysis in treating deep vein thrombosis with congenital absence of the inferior vena cava The patient presented with disabling bilateral lower extremity swelling and pain and was found to have extensive bilateral iliofemoral deep vein thromboses. Genetic testing revealed a factor V Leiden mutation. The patient underwent thrombolysis using a Possis (MEDRAD Inc, Warrendale, Pa) catheter and overnight infusion of tissue plasminogen activator. The patient tolerated the procedure well, with prompt return to daily activities. He remains free of symptoms at 3 years on oral anticoagulation, with a patent venous architecture.
Authors:
Karan Garg; Neal Cayne; Glenn Jacobowitz
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of vascular surgery     Volume:  53     ISSN:  1097-6809     ISO Abbreviation:  J. Vasc. Surg.     Publication Date:  2011 Jun 
Date Detail:
Created Date:  2011-05-25     Completed Date:  2011-08-15     Revised Date:  2012-10-03    
Medline Journal Info:
Nlm Unique ID:  8407742     Medline TA:  J Vasc Surg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1707-10     Citation Subset:  IM    
Copyright Information:
Copyright © 2011 Society for Vascular Surgery. All rights reserved.
Affiliation:
Department of Surgery, New York University Langone Medical Center, New York, NY 10016, USA. karan.garg@nyumc.org
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MeSH Terms
Descriptor/Qualifier:
Adult
Anticoagulants / administration & dosage
Catheterization, Peripheral
Fibrinolytic Agents / administration & dosage
Humans
Male
Thrombolytic Therapy*
Tissue Plasminogen Activator / administration & dosage
Vascular Malformations / complications*
Vena Cava, Inferior / abnormalities*
Venous Thrombosis / etiology,  therapy*
Chemical
Reg. No./Substance:
0/Anticoagulants; 0/Fibrinolytic Agents; EC 3.4.21.68/Tissue Plasminogen Activator

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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