Document Detail


Mechanical output impedance of the lung determined from cardiogenic oscillations.
MedLine Citation:
PMID:  11457803     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The beating heart naturally oscillates the lung because of the close juxtaposition between these organs producing cardiogenic oscillations in flow that can be measured at the mouth when the glottis is open. Correspondingly, if the mouth is occluded, the same phenomenon produces cardiogenic pressure oscillations that can be measured just distal to the site of occlusion. The Fourier-domain ratio of these oscillations in pressure and flow constitutes what we call cardiogenic respiratory impedance (Zc). We calculated Zc between about 1.5 and 10 Hz in relaxed normal subjects at functional residual capacity with open glottis. Zc was insensitive to heart rate changes induced by exercise and had an imaginary part close to zero at all frequencies investigated. Its real part was similar to or smaller than resistance determined by the forced oscillation technique. We speculate that Zc measures the flow resistance of the central and upper airways of the lung. Zc may be useful as a means of obtaining information about lung mechanics without the need for an external source of flow perturbations.
Authors:
E Bijaoui; P F Baconnier; J H Bates
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of applied physiology (Bethesda, Md. : 1985)     Volume:  91     ISSN:  8750-7587     ISO Abbreviation:  J. Appl. Physiol.     Publication Date:  2001 Aug 
Date Detail:
Created Date:  2001-07-17     Completed Date:  2001-09-27     Revised Date:  2013-09-26    
Medline Journal Info:
Nlm Unique ID:  8502536     Medline TA:  J Appl Physiol (1985)     Country:  United States    
Other Details:
Languages:  eng     Pagination:  859-65     Citation Subset:  IM    
Affiliation:
Meakins-Christie Laboratories, McGill University, Montreal, Quebec, Canada H2X 2P2.
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MeSH Terms
Descriptor/Qualifier:
Adult
Airway Resistance / physiology
Exercise / physiology
Female
Fourier Analysis
Heart / physiology*
Heart Rate / physiology*
Humans
Lung / physiology*
Male
Models, Biological
Oscillometry
Physical Exertion / physiology
Reference Values
Respiratory Mechanics / physiology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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