| Mechanical effects of heart contraction on coronary flow. | |
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MedLine Citation:
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PMID: 1182727 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The mechanical effects of heart contraction on coronary flow were studied in the dog heart by implanting vessels in the subendocardial and subepicardial layers of the left ventricular wall and perfusing them independetly of the aortic pressure. At a perfusion pressure of 4 kPa (30 mm Hg), with spontaneous aortic pressure and heart rate, subendocardial flow was 40% less than subepicardial flow. Increasing the aortic pressure or the heart rate produced a comparatively larger decrease of the subendocardial flow. The results suggest that these changes are due to variations of the period of systolic time during which the vessels remain close. |
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Authors:
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R J Domenech; De La Prida |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Cardiovascular research Volume: 9 ISSN: 0008-6363 ISO Abbreviation: Cardiovasc. Res. Publication Date: 1975 Jul |
Date Detail:
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Created Date: 1976-01-30 Completed Date: 1976-01-30 Revised Date: 2008-11-21 |
Medline Journal Info:
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Nlm Unique ID: 0077427 Medline TA: Cardiovasc Res Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 509-14 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Blood Pressure Coronary Circulation* Dogs Electric Stimulation Heart Rate Myocardial Contraction* Perfusion Regional Blood Flow Ventricular Function |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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