Document Detail

Mechanical blood-tissue interaction in contracting muscles: a model study.
MedLine Citation:
PMID:  9727337     Owner:  NLM     Status:  MEDLINE    
A finite element (FE) model of blood perfused biological tissue has been developed. Blood perfusion is described by fluid flow through a series of 5 intercommunicating vascular compartments that are embedded in the tissue. Each compartment is characterized by a blood flow permeability tensor, blood volume fraction and vessel compliance. Local non-linear relationships between intra-extra vascular pressure difference and blood volume fraction, and between blood volume fraction and the permeability tensor, are included in the FE model. To test the implementation of these non-linear relations, FE results of blood perfusion in a piece of tissue that is subject to increased intramuscular pressure, are compared to results that are calculated with a lumped parameter (LP) model of blood perfusion. FE simulation of blood flow through a contracting rat calf muscle is performed. The FE model used in this simulation contains a transversely isotropic, non-linearly elastic description of deforming muscle tissue, in which local contraction stress is prescribed as a function of time. FE results of muscle tension, total arterial inflow and total venous outflow of the muscle during contraction, correspond to experimental results of an isometrically and tetanically contracting rat calf muscle.
W J Vankan; J M Huyghe; C C van Donkelaar; M R Drost; J D Janssen; A Huson
Related Documents :
24558047 - Indocyanine green fluorescent dye during bowel surgery: are the blood supply "guessing ...
3575907 - Origins and regional distribution of blood flow to the respiratory muscles in conscious...
6725887 - Evaluation of vascular compromise in the injured extremity: a photoplethysmographic tec...
23096177 - Perfusion mdct of prostate cancer: correlation of perfusion ct parameters and immunohis...
9140887 - Figuring out why we breathe.
18297137 - Inhibition of neurogenic inflammation as a novel treatment for ischemic stroke.
Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of biomechanics     Volume:  31     ISSN:  0021-9290     ISO Abbreviation:  J Biomech     Publication Date:  1998 May 
Date Detail:
Created Date:  1998-11-17     Completed Date:  1998-11-17     Revised Date:  2009-11-11    
Medline Journal Info:
Nlm Unique ID:  0157375     Medline TA:  J Biomech     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  401-9     Citation Subset:  IM    
Department of Mechanical Engineering, Eindhoven University of Technology, Netherlands.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Arteries / physiology
Blood Pressure / physiology
Blood Volume / physiology
Capillary Permeability / physiology
Computer Simulation
Finite Element Analysis*
Isometric Contraction / physiology
Models, Biological
Muscle Contraction / physiology*
Muscle, Skeletal / blood supply*
Nonlinear Dynamics
Regional Blood Flow / physiology
Stress, Mechanical
Vascular Capacitance / physiology
Veins / physiology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Evaluation of certain veterinary drug residues in food. Forty-eighth report of the Joint FAO/WHO Exp...
Next Document:  Steady flow dynamics of prosthetic aortic heart valves: a comparative evaluation with PIV techniques...