Document Detail

Measuring secretion in chromaffin cells using electrophysiological and electrochemical methods.
MedLine Citation:
PMID:  18021323     Owner:  NLM     Status:  MEDLINE    
Our present understanding of exocytosis of catecholamines has benefited tremendously from the arrival of single-cell electrochemical methods (amperometry and voltammetry), electrophysiological techniques (whole-cell and patch capacitance) and from the combination of both techniques (patch amperometry). In this brief review, we will outline the strengths and limitations of amperometric and electrophysiological methods and highlight the major contribution obtained with the use of these techniques in chromaffin cells.
R Borges; M Camacho; K D Gillis
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review     Date:  2007-11-16
Journal Detail:
Title:  Acta physiologica (Oxford, England)     Volume:  192     ISSN:  1748-1716     ISO Abbreviation:  Acta Physiol (Oxf)     Publication Date:  2008 Feb 
Date Detail:
Created Date:  2008-01-31     Completed Date:  2008-04-11     Revised Date:  2009-02-03    
Medline Journal Info:
Nlm Unique ID:  101262545     Medline TA:  Acta Physiol (Oxf)     Country:  England    
Other Details:
Languages:  eng     Pagination:  173-84     Citation Subset:  IM    
Unidad de Farmacología, Facultad de Medicina, Universidad de La Laguna, Tenerife, Spain.
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MeSH Terms
Cells, Cultured
Chromaffin Cells / secretion*
Chromaffin Granules / physiology
Patch-Clamp Techniques
Grant Support

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