| Measuring pressure-derived fractional flow reserve through four French diagnostic catheters. | |
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MedLine Citation:
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PMID: 12714149 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Measurement of fractional flow reserve (FFR) with a pressure wire is used to discriminate between patients with and without functionally significant lesions. FFR can be assessed through a conventional 4Fr diagnostic catheter, which is a more convenient method of assessment. The aim of this study was to assess the feasibility, safety, repeatability, and reliability of routine FFR measurements through 4Fr diagnostic catheters. From a single-center prospective registry, results of FFR assessment through a 4Fr catheter were used to determine: (1) feasibility and safety, by the procedural success rate and immediate and 30-day clinical outcome; (2) repeatability, by the intraclass correlation coefficient and comparison of the difference (means +/- 2 SDs); and (3) reliability, by comparison of results obtained using 4Fr versus 7Fr guiding catheters. During the study period, FFR was measured in 190 patients, in 122 using a diagnostic 4Fr catheter (study population) and in 68 using a 7Fr guiding catheter. Measurement of FFR wa successful in 115 of 122 patients (94%). No complications related to the use of the 4Fr catheter occurred. Repeatability was determined from 108 repeated measurements: the intraclass correlation coefficient was 0.942 and the mean difference between repeated FFR measurements was -0.001 +/- 0.038. Reliability was determined from 15 unselected patients; there was no systematic error and only 1 value was out of the range of 2 SDs of the mean difference. Using a threshold value of 0.75, the Kappa coefficient for the qualitative agreement was 0.84. Thus, pressure-derived FFR assessment can safely be performed through 4Fr diagnostic catheters, with similar repeatability and reliability as 7Fr guiding catheters, resulting in a simplification of the measurement procedure. |
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Authors:
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Pierre Legalery; Marie-France Seronde; Nicolas Meneveau; François Schiele; Jean-Pierre Bassand |
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Publication Detail:
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Type: Evaluation Studies; Journal Article |
Journal Detail:
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Title: The American journal of cardiology Volume: 91 ISSN: 0002-9149 ISO Abbreviation: Am. J. Cardiol. Publication Date: 2003 May |
Date Detail:
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Created Date: 2003-04-25 Completed Date: 2003-05-23 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0207277 Medline TA: Am J Cardiol Country: United States |
Other Details:
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Languages: eng Pagination: 1075-8 Citation Subset: AIM; IM |
Affiliation:
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University Hospital Jean-Minjoz, Besançon, France |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Coronary Angiography Coronary Circulation Coronary Disease / diagnosis*, physiopathology, radiography Feasibility Studies Female Heart Catheterization / instrumentation* Humans Male Middle Aged Pressure Reproducibility of Results |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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