Document Detail


Measuring placental transfusion for term births: weighing babies with cord intact.
MedLine Citation:
PMID:  21083868     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: To estimate the volume and duration of placental transfusion at term.
DESIGN: Prospective observational study.
SETTING: Maternity unit in Bradford, UK.
POPULATION: Twenty-six term births.
METHODS: Babies were weighed with umbilical cord intact using digital scales that record an average weight every 2 seconds. Placental transfusion was calculated from the change in weight between birth and either cord clamping or when weighing stopped. Start and end weights were estimated using both a B-spline and inspection of graphs. Weight was converted to volume, 1 ml of blood weighing 1.05 g.
MAIN OUTCOME MEASURES: Volume and duration of placental transfusion.
RESULTS: Twenty-six babies were weighed. Start weights were difficult to determine because of artefacts in the data as the baby was placed on the scales and wrapped. The mean difference in weight was 116 g [95% confidence interval (CI), 72-160 g] using the B-spline and 87 g (95% CI, 64-110 g) using inspection. Converting this to the mean volume of placental transfusion gave 110 ml (95% CI, 69-152 ml) and 83 ml (95% CI, 61-106 ml), respectively. Placental transfusion was usually complete by 2 minutes, but sometimes continued for up to 5 minutes. Based on the B-spline, placental transfusion contributed 32 ml (95% CI, 30-33 ml) per kilogram of birth weight to blood volume, but 24 ml (95% CI, 19-32 ml) based on inspection. This equates to 40% (95% CI, 37-42%) and 30% (24-40%), respectively, of total potential blood volume.
CONCLUSION: Inspection of the graphs probably underestimates placental transfusion. For term infants, placental transfusion contributes between one-third and one-quarter of total potential blood volume at birth.
Authors:
D Farrar; R Airey; G R Law; D Tuffnell; B Cattle; L Duley
Related Documents :
2169368 - Effects of isosorbide dinitrate on the pattern of arterial blood flow in healthy human ...
8969788 - Indexes of flow and cross-sectional area of the middle cerebral artery using doppler ul...
11948568 - Changes in blood flow velocity in the middle and anterior cerebral arteries evoked by w...
9070138 - The deep venous system in the puerperium: an ultrasound study.
6609228 - Serial measurement of regional cerebral blood flow in patients with sah using 133xe inh...
10735458 - The inaccuracy of venous and capillary blood glucose measurement using reagent strips i...
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2010-11-18
Journal Detail:
Title:  BJOG : an international journal of obstetrics and gynaecology     Volume:  118     ISSN:  1471-0528     ISO Abbreviation:  BJOG     Publication Date:  2011 Jan 
Date Detail:
Created Date:  2010-12-14     Completed Date:  2011-02-02     Revised Date:  2011-05-25    
Medline Journal Info:
Nlm Unique ID:  100935741     Medline TA:  BJOG     Country:  England    
Other Details:
Languages:  eng     Pagination:  70-5     Citation Subset:  AIM; IM    
Copyright Information:
© 2010 The Authors Journal compilation © RCOG 2010 BJOG An International Journal of Obstetrics and Gynaecology.
Affiliation:
Bradford Institute for Health Research, Bradford Royal Infirmary, Bradford, UK. diane.farrar@bradfordhospitals.nhs.uk
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Birth Weight / physiology*
Blood Volume / physiology
Cesarean Section
Constriction
Delivery, Obstetric
Female
Humans
Labor Stage, First / physiology
Placenta / blood supply*
Pregnancy
Prospective Studies
Term Birth / physiology*
Time Factors
Comments/Corrections
Comment In:
BJOG. 2011 May;118(6):767; author reply 767-7   [PMID:  21481142 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Left ventricular function many years after recovery from pre-eclampsia.
Next Document:  Is ionic dialysance useful for early detection of vascular access dysfunction? Six illustrative case...