Document Detail


Measuring neutrophil functions might be a good predictive marker of overtraining in athletes.
MedLine Citation:
PMID:  18452137     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In order to develop a predictive marker of overtraining in athletes, we examined the changes in neutrophil function [reactive oxygen species (ROS) production capability and phagocytic activity (PA)] for 10 male and 13 female judoists attending a training camp. Measurements were taken four times in total--immediately before and after a 2 h unified exercise loading (UEL) performed 1 day before (Pre-Camp) and the day after the 7 day training camp (Post-Camp). UEL-mediated aspartate aminotransferase was higher at Post-Camp than at Pre-Camp in females but not in males. Post-Camp leukocyte/neutrophil counts after the UEL significantly increased in females but not in males. The rate of change in C4 was significantly smaller in females than in males at Post-Camp. Only ROS significantly decreased without any compensation (increase in PA) being made at Post-Camp in females. In conclusion, this finding, namely that ROS significantly decreased only at Post-Camp without any compensatory mechanism (increase in PA), would suggest that the training camp imposed greater loading on females than males. This consideration was supported by the atypical aspartate aminotransferase, leukocyte/neutrophil counts and C4 findings which were seen at Post-Camp only in females. Therefore, regularly examining neutrophil functions such as ROS and PA might be a good preventative measure against overtraining in athletes participating in training camps.
Authors:
Makoto Yaegaki; Takashi Umeda; Ippei Takahashi; Yousuke Yamamoto; Arata Kojima; Masaru Tanabe; Kiyonori Yamai; Masashi Matsuzaka; Norio Sugawara; Shigeyuki Nakaji
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Luminescence : the journal of biological and chemical luminescence     Volume:  23     ISSN:  1522-7243     ISO Abbreviation:  Luminescence     Publication Date:    2008 Sep-Oct
Date Detail:
Created Date:  2008-09-24     Completed Date:  2008-11-04     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100889025     Medline TA:  Luminescence     Country:  England    
Other Details:
Languages:  eng     Pagination:  281-6     Citation Subset:  IM    
Affiliation:
Department of Social Medicine, Hirosaki University Graduate School of Medicine, Zaifu-cho 5, Hirosaki, Aomori 036-8562, Japan.
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MeSH Terms
Descriptor/Qualifier:
Adult
Biological Markers
Female
Humans
Male
Martial Arts
Neutrophils / metabolism,  physiology*
Phagocytes / immunology,  metabolism
Physical Education and Training / standards*
Predictive Value of Tests*
Reactive Oxygen Species / analysis
Sex Factors
Chemical
Reg. No./Substance:
0/Biological Markers; 0/Reactive Oxygen Species

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