Document Detail


Measuring the microbiome: perspectives on advances in DNA-based techniques for exploring microbial life.
MedLine Citation:
PMID:  22308073     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
This article reviews recent advances in 'microbiome studies': molecular, statistical and graphical techniques to explore and quantify how microbial organisms affect our environments and ourselves given recent increases in sequencing technology. Microbiome studies are moving beyond mere inventories of specific ecosystems to quantifications of community diversity and descriptions of their ecological function. We review the last 24 months of progress in this sort of research, and anticipate where the next 2 years will take us. We hope that bioinformaticians will find this a helpful springboard for new collaborations with microbiologists.
Authors:
James A Foster; John Bunge; Jack A Gilbert; Jason H Moore
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Review     Date:  2012-02-04
Journal Detail:
Title:  Briefings in bioinformatics     Volume:  13     ISSN:  1477-4054     ISO Abbreviation:  Brief. Bioinformatics     Publication Date:  2012 Jul 
Date Detail:
Created Date:  2012-07-26     Completed Date:  2012-12-04     Revised Date:  2013-06-26    
Medline Journal Info:
Nlm Unique ID:  100912837     Medline TA:  Brief Bioinform     Country:  England    
Other Details:
Languages:  eng     Pagination:  420-9     Citation Subset:  IM    
Affiliation:
Department of Biological Sciences, Institute for Bioinformatics and Evolutionary Studies, University of Idaho, Moscow, ID 83844-3051, USA. foster@uidaho.edu
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MeSH Terms
Descriptor/Qualifier:
DNA / chemistry*
Ecosystem
Genomics / methods*
Metagenome*
Grant Support
ID/Acronym/Agency:
AI59694/AI/NIAID NIH HHS; LM009012/LM/NLM NIH HHS; LM010098/LM/NLM NIH HHS; P20RR016454/RR/NCRR NIH HHS; P20RR16448/RR/NCRR NIH HHS
Chemical
Reg. No./Substance:
9007-49-2/DNA
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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