Document Detail

Measuring the impact of cataract surgery on generic and vision-specific quality of life.
MedLine Citation:
PMID:  23015266     Owner:  NLM     Status:  MEDLINE    
PURPOSE: Cataracts are the leading cause of blindness worldwide and cause visual impairment for millions of adults in the United States. We compared the sensitivity of a vision-specific health-related quality of life (HRQOL) measure to that of multiple generic measures of HRQOL before and at 2 time points after cataract surgery.
METHODS: Participants completed 1 vision-specific and 5 generic quality of life measures before cataract surgery, and again 1 and 6 months after surgery. Random effects modeling was used to measure changes over the three assessment points.
RESULTS: The NEI-VFQ25 total score and all 11 subscales showed significant improvements during the first interval (baseline and 1 month). During the second interval (1-6 months post-surgery), significant improvements were observed on the total score and 5 of 11 NEI-VFQ25 subscales. There were significant increases in HRQOL during the first interval on some preference-based generic HRQOL measures, though changes during the second interval were mostly non-significant. None of the SF-36v2™ or SF6D scales changed significantly between any of the assessment periods.
CONCLUSIONS: The NEI-VFQ25 was sensitive to changes in vision-specific domains of QOL. Some preference-based generic HRQOL measures were also sensitive to change and showed convergence with the NEI-VFQ25, but the effects were small. The SF-36v2™ and SF-6D did not change in a similar manner, possibly reflecting a lack of vision-related content. Studies seeking to document both the vision-specific and generic HRQOL improvements of cataract surgery should consider these results when selecting measures.
Erik J Groessl; Lin Liu; Marisa Sklar; Steven R Tally; Robert M Kaplan; Theodore G Ganiats
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, N.I.H., Extramural     Date:  2012-09-27
Journal Detail:
Title:  Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation     Volume:  22     ISSN:  1573-2649     ISO Abbreviation:  Qual Life Res     Publication Date:  2013 Aug 
Date Detail:
Created Date:  2013-08-02     Completed Date:  2014-05-19     Revised Date:  2014-08-06    
Medline Journal Info:
Nlm Unique ID:  9210257     Medline TA:  Qual Life Res     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  1405-14     Citation Subset:  IM    
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MeSH Terms
Cataract / physiopathology*,  psychology
Cataract Extraction*
Health Status
Middle Aged
Quality of Life*
Sickness Impact Profile
Treatment Outcome
United States
Vision, Ocular
Visual Acuity
Grant Support

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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