Document Detail

Measuring heart rate variability with wavelet thresholds and energy components in healthy subjects and patients with congestive heart failure.
MedLine Citation:
PMID:  16682791     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Analysis of wavelet thresholds and energy components can be used to differentiate patients with congestive heart failure (CHF) from healthy subjects and to demonstrate the improvement of heart rate variability after treatment with beta-blockers in the patient group. METHODS: Nine patients with CHF without concurrent beta-blocker therapy and 15 healthy volunteers were recruited and received 24-hour Holter recording. Wavelet thresholds and energy components were calculated. The patients with CHF were then treated with atenolol for 3 months. Another Holter recording was repeated and associated wavelet parameters were estimated. RESULTS: Wavelet thresholds were statistically higher in normal subjects than those derived from patients with CHF (62.40 +/- 20.65 vs. 16.90 +/- 9.72, p < 0.001). The difference was still significant after control of heart rate and the total number of heart beats (74.85 +/- 22.68 vs. 32.51 +/- 18.73, p < 0.001). The energy component of HRV in the finest wavelet domain was also significantly higher in the normal subjects (243.01 +/- 237.69 x 10(-6) vs. 40.65 +/- 39.65 x 10(-6), p = 0.001). These two measures increased after treatment with beta-blockers in the patients with CHF, but not to the extent of those of normal subjects. CONCLUSION: Analysis of wavelet thresholds and energy components has provided robust and accurate measurements for background HRV.
Jou-Wei Lin; Juey-Jen Hwang; Liang-Yu Lin; Jiunn-Lee Lin
Publication Detail:
Type:  Controlled Clinical Trial; Journal Article     Date:  2006-05-08
Journal Detail:
Title:  Cardiology     Volume:  106     ISSN:  0008-6312     ISO Abbreviation:  Cardiology     Publication Date:  2006  
Date Detail:
Created Date:  2006-11-19     Completed Date:  2007-02-12     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  1266406     Medline TA:  Cardiology     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  207-14     Citation Subset:  IM    
Copyright Information:
2006 S. Karger AG, Basel
National Taiwan University Hospital Yun-Lin Branch, Yun-Lin, Taiwan, ROC.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Adrenergic beta-Antagonists / therapeutic use
Atenolol / therapeutic use
Electrocardiography, Ambulatory* / drug effects
Energy Metabolism
Heart Failure / diagnosis*,  drug therapy,  physiopathology*
Heart Rate* / drug effects
Middle Aged
Models, Cardiovascular
Reg. No./Substance:
0/Adrenergic beta-Antagonists; 29122-68-7/Atenolol

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Pharmacological studies on fullerene (C60), a novel carbon allotrope, and its derivatives.
Next Document:  Frequency of dementia etiologies in four ethnic groups.