Document Detail


Measuring exercise-induced adaptations and injury with magnetic resonance spectroscopy.
MedLine Citation:
PMID:  1483756     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We compared the metabolic capacity of calf muscles in young normal subjects who performed endurance training to highly trained track athletes, older subjects, and subjects with several metabolic diseases. Metabolic capacity was measured as the rate of phosphocreatine (PCr) recovery following submaximal exercise. PCr levels were measured using magnetic resonance spectroscopy (MRS). Exercise consisted of repeated plantar flexion against resistance. MRS calculated metabolic capacity agreed well with rates from muscle biopsies. Short term endurance training resulted in a 14% increase in metabolic capacity. This adaptation was small compared to the metabolic capacities of endurance athletes (70% greater than control subjects), and changes due to aging (20% and 55% declines by 66 and 80 years of age, respectively). Exercise training is also associated with muscle injury. Muscle injury was seen as a transient elevation of Pi/PCr at rest in response to an acute bout of exercise. The elevation of resting Pi/PCr persisted during continued training. Metabolic capacity as measured by the rate of phosphocreatine recovery increased with endurance training and decreased with normal aging and metabolic disease. Small levels of persistent muscle injury is a natural by product of strenuous endurance training.
Authors:
K McCully; J Posner
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  International journal of sports medicine     Volume:  13 Suppl 1     ISSN:  0172-4622     ISO Abbreviation:  Int J Sports Med     Publication Date:  1992 Oct 
Date Detail:
Created Date:  1993-02-18     Completed Date:  1993-02-18     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8008349     Medline TA:  Int J Sports Med     Country:  GERMANY    
Other Details:
Languages:  eng     Pagination:  S147-9     Citation Subset:  IM; S    
Affiliation:
Department of Geriatric Medicine, Medical College Hospitals, Philadelphia, PA 19129.
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MeSH Terms
Descriptor/Qualifier:
Adaptation, Physiological / physiology*
Adult
Aged
Aged, 80 and over
Aging / metabolism
Exercise / physiology*
Humans
Magnetic Resonance Spectroscopy
Muscles / injuries*,  metabolism*
Phosphocreatine / metabolism
Physical Education and Training
Chemical
Reg. No./Substance:
67-07-2/Phosphocreatine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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