| Measuring cardiac output during dobutamine infusion after off-pump coronary artery bypass: comparison of transesophageal echo-Doppler and thermodilution. | |
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MedLine Citation:
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PMID: 12476476 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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AIM: To compare transesophageal echo-Doppler with thermodilution method for measuring cardiac output during dobutamine infusion after off-pump coronary artery bypass. METHOD: Using transesophageal echo-Doppler and thermodilution methods, we measured cardiac output in 30 patients after off-pump coronary artery bypass, immediately before and 5, 15, and 30 min after the introduction of continuous dobutamine infusion (3 microg/kg/min). Paired t-test and Bland-Altman analysis were used to compare the results obtained by two methods in this prospective study. RESULTS: Significant increase in cardiac output during dobutamine infusion was detected by both thermodilution (from 3.9 +/- 1.0 to 4.6 +/- 1.1 L/min; p < 0.001) and transesophageal echo-Doppler (from 3.8 +/- 1.2 to 4.8 +/- 1.4 L/min; p < 0.001). Initial measurement results of thermodilution and transesophageal echo-Doppler techniques showed clinically acceptable agreement, with a mean difference of only + 0.09 L/min (95% confidence interval (CI), 0.42 to + 0.61). Subsequently repeated measurements after 5, 15, and 30 min showed almost the same agreement between the methods. The highest mean difference between the initial and repeated measurements was found at 5 min after the introduction of dobutamine infusion (-0.29 L/min, 95% CI, -1.06 to + 0.48). CONCLUSION: Transesophageal echo-Doppler and thermodilution can be interchangeable as methods for measuring cardiac output after off-pump coronary artery bypass. |
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Authors:
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Ino Husedzinović; Stjepan Barisin; Dinko Tonković; Sinisa Sostarić |
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Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: Croatian medical journal Volume: 43 ISSN: 0353-9504 ISO Abbreviation: Croat. Med. J. Publication Date: 2002 Dec |
Date Detail:
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Created Date: 2002-12-11 Completed Date: 2003-01-24 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 9424324 Medline TA: Croat Med J Country: Croatia |
Other Details:
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Languages: eng Pagination: 680-4 Citation Subset: IM |
Affiliation:
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Department of Anesthesiology and Intensive Therapy, Dubrava University Hospital, Zagreb, Croatia. kka@kbd.hr |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Cardiotonic Agents / administration & dosage* Coronary Artery Bypass / methods* Coronary Artery Disease / physiopathology, surgery* Croatia Dobutamine / administration & dosage* Echocardiography, Transesophageal* Female Heart Function Tests / methods* Humans Male Middle Aged Thermodilution* |
| Chemical | |
Reg. No./Substance:
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0/Cardiotonic Agents; 34368-04-2/Dobutamine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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