Document Detail


Measuring uptake dynamics of multiple identifiable carbon nanotube species via high-speed confocal Raman imaging of live cells.
MedLine Citation:
PMID:  23151070     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Carbon nanotube uptake was measured via high-speed confocal Raman imaging in live cells. Spatial and temporal tracking of two cell-intrinsic and nine nanotube-derived Raman bands was conducted simultaneously in RAW 264.7 macrophages. Movies resolved single (n, m) species, defects, and aggregation states of nanotubes transiently as well as the cell position, denoted by lipid and protein signals. This work portends the real-time molecular imaging of live cells and tissues using Raman spectroscopy, affording multiplexing and complete photostability.
Authors:
Jeon Woong Kang; Freddy T Nguyen; Niyom Lue; Ramachandra R Dasari; Daniel A Heller
Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't     Date:  2012-11-14
Journal Detail:
Title:  Nano letters     Volume:  12     ISSN:  1530-6992     ISO Abbreviation:  Nano Lett.     Publication Date:  2012 Dec 
Date Detail:
Created Date:  2012-12-12     Completed Date:  2014-02-05     Revised Date:  2014-05-20    
Medline Journal Info:
Nlm Unique ID:  101088070     Medline TA:  Nano Lett     Country:  United States    
Other Details:
Languages:  eng     Pagination:  6170-4     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Animals
Biological Transport
Cell Line
Macrophages / cytology*,  metabolism
Mice
Microscopy, Confocal / methods*
Molecular Imaging / methods
Nanotubes, Carbon / analysis*
Spectrum Analysis, Raman / methods*
Grant Support
ID/Acronym/Agency:
P41 EB015871/EB/NIBIB NIH HHS; P41EB015871-26A1/EB/NIBIB NIH HHS
Chemical
Reg. No./Substance:
0/Nanotubes, Carbon
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Live virus-free or die: coupling of antivirus immunity and programmed suicide or dormancy in prokary...
Next Document:  Incidence, Clinical Features, Laboratory Findings and Outcome of Multiple Myeloma Patients Presentin...