| Measurements of ultrasonic attenuation properties of midgestational fetal pig hearts. | |
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MedLine Citation:
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PMID: 18977067 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The objectives of this study were to measure the relative attenuation properties of the left and right ventricles in fetal pig hearts and to compare the spatial variation in attenuation measurements with those observed in previously published backscatter measurements. Approximately 1.0-mm-thick, short-axis slices of excised, formalin-fixed heart were examined from 15 midgestational fetal pigs using a 50-MHz single-element transducer. Measurements of the attenuation properties demonstrate regional differences in the left and right ventricular myocardium that appear consistent with the previously reported regional differences in apparent integrated backscatter measurements of the same fetal pig hearts. For regions of perpendicular insonification relative to the myofiber orientation, the right ventricular free wall showed larger values for the slope of the attenuation coefficient from 30-60 MHz (1.48 +/- 0.22 dB/(cm x MHz) (mean +/- SD) and attenuation coefficient at 45 MHz (46.3 +/- 7.3 dB/cm [mean +/- SD]) than the left ventricular free wall (1.18 +/- 0.24 dB/(cm x MHz) and 37.0 +/- 7.9 dB/cm (mean +/- SD) for slope of attenuation coefficient and attenuation coefficient at 45 MHz, respectively). This attenuation study supports the hypothesis that intrinsic differences in the myocardium of the left and right ventricles exist in fetal pig hearts at midgestation. |
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Authors:
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Allyson A Gibson; Gautam K Singh; Joseph J Hoffman; Achiau Ludomirsky; Mark R Holland |
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Publication Detail:
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Type: Journal Article; Research Support, N.I.H., Extramural Date: 2008-10-31 |
Journal Detail:
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Title: Ultrasound in medicine & biology Volume: 35 ISSN: 1879-291X ISO Abbreviation: Ultrasound Med Biol Publication Date: 2009 Feb |
Date Detail:
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Created Date: 2009-01-23 Completed Date: 2009-03-02 Revised Date: 2011-06-06 |
Medline Journal Info:
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Nlm Unique ID: 0410553 Medline TA: Ultrasound Med Biol Country: England |
Other Details:
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Languages: eng Pagination: 319-28 Citation Subset: IM |
Affiliation:
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Laboratory for Ultrasonics, Washington University, St. Louis, MO 63130, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Fetal Heart / ultrasonography* Gestational Age Heart Ventricles Image Interpretation, Computer-Assisted* Scattering, Radiation Swine / embryology* Ultrasonography, Prenatal / methods, veterinary |
| Grant Support | |
ID/Acronym/Agency:
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R01 HL040302/HL/NHLBI NIH HHS; R01 HL040302-21/HL/NHLBI NIH HHS; R01 HL040302-24/HL/NHLBI NIH HHS |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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