Document Detail

Measurement of venous oxyhaemoglobin saturation in the adult human forearm by near infrared spectroscopy with venous occlusion.
MedLine Citation:
PMID:  9327608     Owner:  NLM     Status:  MEDLINE    
Measurement of the oxygenation of the peripheral tissues provides useful information about tissue perfusion. A method is described for the measurement of peripheral venous oxyhaemaglobin saturation (SvO2) in the adult forearm by a noninvasive technique, near infrared spectroscopy (NIRS) with venous occlusion. A series of studies is performed on healthy adults to compare measurements of forearm SvO2 made by NIRS with measurements of superficial venous SvO2 made by co-oximetry, and to study the effect of different optode spacings. There is a significant correlation between forearm SvO2 measured by NIRS and SvO2 of superficial venous blood measured by co-oximetry (n = 19, r = 0.7, p < 0.0001). Higher values for SvO2 were obtained using a 2.5 cm spacing than with a 4 cm spacing (mean difference = 4.1% (95% CI 1.4%-6.8%) n = 16). This difference is likely to have been due to a more superficial volume of tissue being studied with the closer optode spacing. Peripheral SvO2 can be measured non-invasively using NIRS with venous occlusion. It may prove to be a useful method to study circulatory disturbances.
C W Yoxall; A M Weindling
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Medical & biological engineering & computing     Volume:  35     ISSN:  0140-0118     ISO Abbreviation:  Med Biol Eng Comput     Publication Date:  1997 Jul 
Date Detail:
Created Date:  1997-10-23     Completed Date:  1997-10-23     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7704869     Medline TA:  Med Biol Eng Comput     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  331-6     Citation Subset:  IM    
Department of Child Health, University of Liverpool, UK.
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MeSH Terms
Forearm / blood supply*
Middle Aged
Oxyhemoglobins / metabolism*
Regional Blood Flow
Spectroscopy, Near-Infrared
Reg. No./Substance:

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