Document Detail

Measurement and validity of the ventilatory threshold in patients with congenital heart disease.
MedLine Citation:
PMID:  8778709     Owner:  NLM     Status:  MEDLINE    
The purpose of the present study was to measure oxygen uptake (VO2) at the ventilatory threshold (VT) in patients with congenital heart disease using a progressive exercise protocol on a treadmill and to evaluate the validity and feasibility of this procedure. Eight control subjects and seventeen patients performed a maximal exercise test with breath-by-breath measurement of ventilation and gas exchange variables. VT(VE) was determined by the change in the ventilatory equivalent for VO2 and carbon dioxide output, VT(V-sl) by the V-slope method, and the lactate threshold (LT) by the change in blood lactate concentration; these parameters were determined in 100%, 88%, and 96% of subjects, respectively. The interobserver error among three evaluators was not significant, and LT was correlated with each VT (r = 0.97, 0.92; p = 0.0001) and with peak VO2 (r = 0.91; p = 0.0001). The VTs were correlated with each other when expressed as milliliter per minute and milliliters per kilogram per minute. It was concluded that a progressive exercise protocol on a treadmill was a feasible procedure for determining the VTs in most individuals and that VTs were valid, useful parameters for evaluating submaximal exercise tolerance in patients with congenital heart disease.
H Ohuchi; T Nakajima; M Kawade; M Matsuda; T Kamiya
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Publication Detail:
Type:  Clinical Trial; Controlled Clinical Trial; Journal Article    
Journal Detail:
Title:  Pediatric cardiology     Volume:  17     ISSN:  0172-0643     ISO Abbreviation:  Pediatr Cardiol     Publication Date:    1996 Jan-Feb
Date Detail:
Created Date:  1996-09-16     Completed Date:  1996-09-16     Revised Date:  2008-02-20    
Medline Journal Info:
Nlm Unique ID:  8003849     Medline TA:  Pediatr Cardiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  7-14     Citation Subset:  IM    
Department of Pediatrics, National Cardiovascular Center, Osaka, Japan.
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MeSH Terms
Anaerobic Threshold*
Analysis of Variance
Blood Gas Analysis
Exercise Test / methods
Exercise Tolerance / physiology*
Heart Defects, Congenital / physiopathology*
Lactates / blood
Linear Models
Observer Variation
Oxygen Consumption
Pulmonary Gas Exchange
Reproducibility of Results
Reg. No./Substance:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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