Document Detail


Measurement of transcutaneous hemoglobin concentration by noninvasive white-light spectroscopy in infants.
MedLine Citation:
PMID:  16199691     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: To compare transcutaneously spectroscopically measured hemoglobin values with venous hemoglobin values in infants. STUDY DESIGN: Prospective study in healthy preterm and term infants who were breathing spontaneously. RESULTS: Recordings were obtained from 85 stable infants (median gestational age at measurement: 36 weeks [range: 34-43 weeks]; median body weight: 1890 g [range: 1095-4360 g]). The spectroscopic hemoglobin values were corrected for inhomogeneous distribution of hemoglobin in the tissue. The venous and spectroscopic hemoglobin values were then compared by using the Bland-Altman method, which gave an error of <5%. CONCLUSIONS: This pilot study could illustrate a good relation between the 2 methods for measuring hemoglobin. Larger studies are required to validate the spectroscopic method in those with conditions that affect the skin microcirculation (eg, septicemia).
Authors:
Heike Rabe; Natascha Stupp; Murat Ozgün; Erik Harms; Holger Jungmann
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Pediatrics     Volume:  116     ISSN:  1098-4275     ISO Abbreviation:  Pediatrics     Publication Date:  2005 Oct 
Date Detail:
Created Date:  2005-10-03     Completed Date:  2005-12-28     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0376422     Medline TA:  Pediatrics     Country:  United States    
Other Details:
Languages:  eng     Pagination:  841-3     Citation Subset:  AIM; IM    
Affiliation:
Department of Neonatology, Brighton and Sussex University Hospitals NHS Trust, Brighton BN2 5BE, United Kingdom. heike.rabe@bsuh.nhs.uk
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MeSH Terms
Descriptor/Qualifier:
Capillaries
Gestational Age
Hemoglobins / analysis*
Humans
Infant, Newborn
Infant, Premature
Microcirculation
Skin / blood supply*
Spectrum Analysis* / instrumentation,  methods
Veins
Chemical
Reg. No./Substance:
0/Hemoglobins

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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