| Measurement of the time course of optical quality and visual deterioration during tear break-up. | |
| | |
MedLine Citation:
|
PMID: 20107168 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
PURPOSE: To compare changes in optical quality and visual performance that accompany tear break-up (TBU) during blink suppression. METHODS: A three-channel optical system was developed that simultaneously measured refractive aberrations (Shack-Hartmann aberrometer), 20/40 letter contrast sensitivity (CS), and TBU (retroillumination, RI). Ten wearers of silicone hydrogel contact lenses were asked to keep one eye open for approximately 18 seconds, while CS, wavefront aberrations, and RI images were collected. The wavefront was reconstructed by zonal methods, and image quality was quantified with a series of metrics including RMS fit error. Novel metrics for quantifying TBU over the contact lens surface were developed by quantifying the contrast of the RI image and by using Fourier descriptors of the first Purkinje (PJ) image shape. RESULTS: There was a full range of TBU over the lens surface, with four subjects showing TBU across the corneal center and one subject with TBU in the inferior peripheral pupil. Among the four subjects with central corneal TBU, RMS fit error, RI contrast, and PJ Fourier descriptors showed high correlation with CS (r(2) range, 0.9187-0.9414, 0.6261-0.975, and 0.4917-0.8986, respectively). Some of the general optical-quality metrics such as blur strength, neural sharpness, and area of modulation transfer function (MTF) also showed that change correlated with CS loss. CONCLUSIONS: Optical metrics of tear quality and retinal image quality are associated with the decline in vision that occurs with TBU. The evidence supports the hypothesis that blurry vision symptoms reported by contact lens wearers are caused by poor quality of the retinal image due to TBU. |
| | |
Authors:
|
Haixia Liu; Larry Thibos; Carolyn G Begley; Arthur Bradley |
Related Documents
:
|
20967078 - Maxwell fish-eye and eaton lenses emulated by microdroplets. 19933178 - Ultrahigh-resolution measurement by optical coherence tomography of dynamic tear film c... 20076338 - A catadioptric coronagraph design. 20706438 - Imaging and radiometric properties of microlens arrays. 11112828 - The aapm/rsna physics tutorial for residents: fluoroscopy: optical coupling and the vid... 21978048 - Clinical accuracy of exactrac intracranial frameless stereotactic system. |
Publication Detail:
|
Type: Comparative Study; Journal Article Date: 2010-01-27 |
Journal Detail:
|
Title: Investigative ophthalmology & visual science Volume: 51 ISSN: 1552-5783 ISO Abbreviation: Invest. Ophthalmol. Vis. Sci. Publication Date: 2010 Jun |
Date Detail:
|
Created Date: 2010-05-20 Completed Date: 2010-06-11 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 7703701 Medline TA: Invest Ophthalmol Vis Sci Country: United States |
Other Details:
|
Languages: eng Pagination: 3318-26 Citation Subset: IM |
Affiliation:
|
School of Optometry, Indiana University, Bloomington, Indiana 47405, USA. hailiu@indiana.edu |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Aberrometry Adult Contact Lenses, Hydrophilic Contrast Sensitivity / physiology* Corneal Wavefront Aberration / physiopathology Dry Eye Syndromes / physiopathology* Female Fourier Analysis Humans Male Middle Aged Tears / metabolism* Time Factors Vision Disorders / physiopathology* Visual Acuity / physiology Young Adult |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Release of Interleukins 6 and 8 Induced by Zymosan and Mediated by MAP Kinase and NF-{kappa}B Signal...
Next Document: Reduced nitro-oxidative stress and neural cell death suggests a protective role for microglial cells...