| Measurement of thyroid blood flow area is useful for diagnosing the cause of thyrotoxicosis. | |
| | |
MedLine Citation:
|
PMID: 16356088 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
We have utilized color Doppler ultrasonography (CDU) to evaluate the thyroid blood flow area (TBFA) quantitatively, and we propose criteria to differentiate Graves' disease (GD) and destruction-induced thyrotoxicosis (DT) in patients with thyrotoxicosis. We studied 32 patients with diffuse toxic goiter, 21 with GD in the euthyroid state, 12 with chronic thyroiditis in the euthyroid state, and 31 normal individuals. TBFA was calculated as (thyroid blood flow area/thyroid area) x 100%. CDU showed high sensitivity (84%) and specificity (90%) in distinguishing GD from DT when TBFA was between 7.7% and 8.8%. Using CDU to diagnose GD in cases with TBFA >or=8% or positive serum anti-thyrotropin receptor antibody (TRAb), the sensitivity was 95% and the specificity was 90%, which are similar results to those obtained when GD was diagnosed by radioactive iodine uptake (sensitivity 100%, specificity 90%). Therefore, CDU is a more useful and economical method of distinguishing GD patients with TBFA of 8% or above from DT than measurement of TRAb or radioactive iodine uptake. |
| | |
Authors:
|
Seiichiro Kurita; Masaru Sakurai; Yuki Kita; Tsuguhito Ota; Hitoshi Ando; Shuichi Kaneko; Toshinari Takamura |
Related Documents
:
|
21253128 - Hematological support of a cancer patient. 11578358 - Prediction of malignancy using transvaginal color flow doppler in patients with gynecol... 10227498 - Association between a focal spared area in the fatty liver and intrahepatic efferent bl... 16189438 - Evaluation of testicular viability by power doppler ultrasonography in experimentally i... 6702728 - Ethanol in sequestered hematomas: quantitative evaluation. 2724918 - A simple method for intravenous injection and blood collection in the chinchilla (chinc... |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Thyroid : official journal of the American Thyroid Association Volume: 15 ISSN: 1050-7256 ISO Abbreviation: Thyroid Publication Date: 2005 Nov |
Date Detail:
|
Created Date: 2005-12-16 Completed Date: 2006-01-31 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 9104317 Medline TA: Thyroid Country: United States |
Other Details:
|
Languages: eng Pagination: 1249-52 Citation Subset: IM |
Affiliation:
|
Department of Diabetes and Digestive Disease, Kanazawa University Graduate School of Medical Science, Ishikawa, Japan. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Female Goiter / diagnosis, radionuclide imaging Humans Male Middle Aged Positron-Emission Tomography Regional Blood Flow / physiology Thyroid Function Tests Thyroid Gland / blood supply*, ultrasonography Thyroiditis, Autoimmune / diagnosis, radionuclide imaging Thyrotoxicosis / diagnosis*, etiology*, ultrasonography Ultrasonography, Doppler, Color |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Pre-incision infiltration of local anesthetic reduces postoperative pain with no effects on bruising...
Next Document: Hypothyroidism might be related to breast cancer in post-menopausal women.