Document Detail


Measurement of six enzymes with the Kodak DTSC Module, a physician's office analyzer.
MedLine Citation:
PMID:  2889544     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We evaluated the performance of the Kodak DTSC Module for determination of alanine aminotransferase (ALT; EC 2.6.1.2), aspartate aminotransferase (2.5.1.2), alkaline phosphatase (3.1.3.1), creatine kinase (2.7.3.2), gamma-glutamyltransferase (2.3.2.2), and lactate dehydrogenase (1.1.1.27). The DTSC is a "special chemistry" accessory for the DT60 analyzer; the same multilayer film technology as that of the Ektachem 700 is used. The overall precision, assessed over a three-month period with two serum-based quality control materials, ranged from 2.2 to 8.0%. DTSC results for patients' specimens correlated well with those by the Technicon RA-1000 analyzer. The performance of the analyzer in linearity and interference studies was satisfactory for clinical use. The DTSC is simple to operate and has no technique-dependent step; it should be useful for the physician's office laboratory.
Authors:
R H Ng; M Altaffer; M O'Neill; H Mukadam; B E Statland
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Clinical chemistry     Volume:  33     ISSN:  0009-9147     ISO Abbreviation:  Clin. Chem.     Publication Date:  1987 Oct 
Date Detail:
Created Date:  1987-11-25     Completed Date:  1987-11-25     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9421549     Medline TA:  Clin Chem     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1911-3     Citation Subset:  IM    
Affiliation:
Department of Laboratory Medicine, University Hospital, Boston University Medical Center, MA 02118.
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MeSH Terms
Descriptor/Qualifier:
Alanine Transaminase / blood
Alkaline Phosphatase / blood
Alkyl and Aryl Transferases*
Autoanalysis / instrumentation*
Bilirubin
Creatine Kinase / blood
Enzymes / blood*
Hemoglobins
Humans
L-Lactate Dehydrogenase / blood
Lipids / blood
Transferases / blood
gamma-Glutamyltransferase / blood
Chemical
Reg. No./Substance:
0/Enzymes; 0/Hemoglobins; 0/Lipids; 635-65-4/Bilirubin; EC 1.1.1.27/L-Lactate Dehydrogenase; EC 2.-/Transferases; EC 2.3.2.2/gamma-Glutamyltransferase; EC 2.5.-/Alkyl and Aryl Transferases; EC 2.5.1.2/thiamin pyridinylase; EC 2.6.1.2/Alanine Transaminase; EC 2.7.3.2/Creatine Kinase; EC 3.1.3.1/Alkaline Phosphatase

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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