Document Detail

Measurement of the renin-angiotensin system in heart failure.
MedLine Citation:
PMID:  11232216     Owner:  NLM     Status:  MEDLINE    
Angiotensin II (ANG II), the effector hormone of the renin-angiotensin system (RAS), has been implicated in the pathophysiology and progression of heart failure. Therefore, the measurement of ANG II has become important to characterize the role of this neurohormone in heart failure. However, because ANG II has been difficult to measure, other components of the RAS have been measured to characterize ANG II production. The RAS components (e.g., renin, angiotensin I-converting enzyme [ACE], angiotensin II) have been measured with a variety of techniques. In this review, RAS physiology and the techniques used to measure the RAS components are discussed. In addition, the advantages and disadvantages of the RAS measurement methods are described.
S D Kim
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Biological research for nursing     Volume:  1     ISSN:  1099-8004     ISO Abbreviation:  Biol Res Nurs     Publication Date:  2000 Jan 
Date Detail:
Created Date:  2001-03-05     Completed Date:  2001-03-22     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  9815758     Medline TA:  Biol Res Nurs     Country:  United States    
Other Details:
Languages:  eng     Pagination:  210-26     Citation Subset:  IM; N    
University of Illinois at Chicago, Department of Medical-Surgical Nursing, USA.
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MeSH Terms
Angiotensin II / blood*,  physiology*
Disease Progression
Heart Failure / blood*,  diagnosis,  physiopathology*
Hemodynamics / physiology
Peptidyl-Dipeptidase A / blood*,  physiology*
Receptors, Angiotensin / physiology
Renin / blood*,  physiology*
Renin-Angiotensin System / physiology*
Reg. No./Substance:
0/Receptors, Angiotensin; 11128-99-7/Angiotensin II; EC A; EC

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