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Measurement of renal volume using respiratory-gated MRI in subjects without known kidney disease: Intraobserver, interobserver, and interstudy reproducibility.
MedLine Citation:
PMID:  20951519     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
OBJECTIVE: Since renal volume is to be considered in managing renal diseases, a reproducible technique is needed. Our aim was to estimate intraobserver, interobserver, and interstudy reproducibility of renal volume measurement in subjects without known kidney disease using magnetic resonance (MR) imaging.
MATERIALS AND METHODS: We studied 20 patients (age range 33-82 years) without known renal disease using 1.5-T MR imaging with a respiratory-gated two-dimensional coronal balanced steady state free precession sequence. Each patient repeated the study after 1h. Two readers independently segmented the area of both kidneys of the first study, subtracting cysts. After 1 week, the first reader segmented the second study and repeated the segmentation of the first study. The volume of each kidney was obtained by multiplying the renal area on each slice by the slice thickness and summing all the partial volumes. Reproducibility was assessed by Bland-Altman and Wilcoxon statistics. The coefficient of repeatability (CoR) was summed to the absolute value of bias; the ratio between this sum and the mean of the two data sets was used as a measure of variability while its complement to 100% was used as a measure of reproducibility.
RESULTS: Acquisition time was 2-3min. Segmentation time was 20-25min. Intraobserver variability results in a CoR of 7ml and in a reproducibility of 95%, interobserver variability 8.8-9.8ml and 87-88%, interstudy variability 9.8-10.6ml and 91-93%, respectively. Considering both the effect of observer and the repetition of the study, the reproducibility was 83-87%.
CONCLUSION: Renal volume measurement by MR imaging is highly reproducible.
Authors:
Giovanni Di Leo; Fabio Di Terlizzi; Nicola Flor; Alberto Morganti; Francesco Sardanelli
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Publication Detail:
Type:  Journal Article     Date:  2010-10-15
Journal Detail:
Title:  European journal of radiology     Volume:  80     ISSN:  1872-7727     ISO Abbreviation:  Eur J Radiol     Publication Date:  2011 Dec 
Date Detail:
Created Date:  2011-11-07     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8106411     Medline TA:  Eur J Radiol     Country:  Ireland    
Other Details:
Languages:  eng     Pagination:  e212-6     Citation Subset:  IM    
Copyright Information:
Copyright © 2010 Elsevier Ireland Ltd. All rights reserved.
Affiliation:
Unità di Radiologia, IRCCS Policlinico San Donato, Piazza E. Malan, 20097 San Donato Milanese, Italy.
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