Document Detail

Measurement of regional pulmonary oedema in man using radioactive water (H215O).
MedLine Citation:
PMID:  779919     Owner:  NLM     Status:  MEDLINE    
Regional extravascular lung water (rELW) has been measured in normal subjects and in patients with left heart diseases using a double-indicator dilution technique and external counting over the chest. Gamma-emitting radioisotopes were injected intravenously, 113Inm as a vascular non-duffusible indicator, and H215O as a freely diffusible indicator. Time activity curves were then recorded over the upper and lower zones of the lung in the supine position with external probes. rELW per unit of blood volume and rELW per unit of blood flow were increased in patients with raised left atrial pressure even in the presence of radiologically clear lung fields. There was a uniform distribution of these ratios between upper and lower zones in normals, whereas in patients rELW was preferentially distributed in the lower zones.
F Fazio; T Jones; C G MacArthur; C G Rhodes; R E Steiner; J M Hughes
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The British journal of radiology     Volume:  49     ISSN:  0007-1285     ISO Abbreviation:  Br J Radiol     Publication Date:  1976 May 
Date Detail:
Created Date:  1976-10-02     Completed Date:  1976-10-02     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0373125     Medline TA:  Br J Radiol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  393-7     Citation Subset:  AIM; IM    
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MeSH Terms
Blood Flow Velocity
Blood Volume
Body Surface Area
Cardiac Output
Lung / physiopathology
Oxygen Radioisotopes*
Pulmonary Edema / diagnosis*
Radioisotope Dilution Technique
Radionuclide Imaging
Time Factors
Water / diagnostic use*
Reg. No./Substance:
0/Oxygen Radioisotopes; 0/Radioisotopes; 7440-74-6/Indium; 7732-18-5/Water

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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