Document Detail

Measurement of fluid volume shifts during hemodialysis by A-mode ultrasonography.
MedLine Citation:
PMID:  10838468     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: The rate of intercompartmental fluid volume changes during hemodialysis (HD) is a major determinant of dialysis-induced hypotension and lacks direct monitoring. The aim of the study was to evaluate the feasibility of tissue thickness (TT) measurement in monitoring the mobilization of interstitial fluids during HD. METHODS: We studied the intradialytic changes in forehead TT and inferior vena cava diameter (IVCD) in 20 patients. Plasma refilling was calculated from changes in hematocrit (Hct) and ultrafiltration rates. RESULTS: During ultrafiltration of 2,437 +/- 117 ml (mean +/- SEM), Hct increased significantly from 27.9 +/- 0.7 to 30.0 +/- 0.9%. IVCD decreased significantly from 9.7 +/- 0.2 to 6.1 +/- 0.4 mm/m(2). We found a simultaneously pronounced reduction in TT from 4. 46 +/- 0.12 to 3.78 +/- 0.12 mm (> or =15.3%) with a significant correlation to plasma refilling (0.613). CONCLUSION: Volume changes in the peripheral shell tissues during HD can be monitored directly and noninvasively by A-mode ultrasound.
J Schumacher; P Rob; B Kreft; A Engelke; M Heringlake; K F Klotz
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Blood purification     Volume:  18     ISSN:  0253-5068     ISO Abbreviation:  Blood Purif.     Publication Date:  2000  
Date Detail:
Created Date:  2000-10-04     Completed Date:  2000-10-04     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8402040     Medline TA:  Blood Purif     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  103-9     Citation Subset:  IM    
Copyright Information:
Copyright 2000 S. Karger AG, Basel
Department of Anesthesiology, Medical University of Lübeck, Germany.
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MeSH Terms
Blood Pressure / physiology
Blood Volume / physiology
Dizziness / etiology
Fluid Shifts / physiology*
Forehead / physiopathology,  ultrasonography
Heart Rate / physiology
Hemodiafiltration / adverse effects*
Hypotension / etiology,  ultrasonography
Middle Aged
Muscle Cramp / etiology
Ultrasonography / methods*
Vena Cava, Inferior / physiopathology,  ultrasonography

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